Research Article, Int J Cardiovasc Res Vol: 2 Issue: 6
ACP1 Genetic Polymorphism and Cardiac Hypertrophy
| Gloria-Bottini F1*, Banci M2, Saccucci P1, Neri A1, Magrini A1 and Bottini E1 | |
| 1Department of Biomedicine and Prevention, University of Rome Tor Vergata, School of Medicine, Rome, Italy | |
| 2Department of Cardiology, Valmontone Hospital, Rome, Italy | |
| Corresponding author : Fulvia Gloria-Bottini Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 100133 Rome, Italy Tel: ++39+6-30889514 E -mail: gloria@med.uniroma2.it |
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| Received: October 08, 2013 Accepted: December 19, 2013 Published: December 25, 2013 | |
| Citation: Gloria-Bottini F, Banci M,Saccucci P, Neri A, Magrini A, Bottini E (2013) ACP1 Genetic Polymorphism and Cardiac Hypertrophy. Int J Cardiovasc Res 2:6. doi:10.4172/2324-8602.1000151 |
Abstract
ACP1 Genetic Polymorphism and Cardiac Hypertrophy
Platelet derived growth factors (PDGFs) exert an important role in contractile function of cardiomyocytes and protection from apoptotic cell death. Since ACP1is able to dephosphorylate PDGF receptors modulating their actions we have investigated the relationship between ACP1 genetic variability and cardiac hypertrophy.
