Research Article, J Virol Antivir Res Vol: 2 Issue: 3
Detection of Rotavirus G3P[22]Genotype in Gnotobiotic Rabbit Model
| Audrey Cilli1*, Claudia M Koike1,2, Neuza M Frazatti-Gallina2 and Maria do Carmo Sampaio Tavares Timenetsky1 |
| 1Adolfo Lutz Institute, Virology Center, Enteric Diseases Laboratory, Av Dr Arnaldo, 355, CEP 01246-902, São Paulo, SP, Brazil |
| 2Butantan Institute, Av Vital Brasil, 1500, CEP São Paulo, SP, Brazil |
| Corresponding author : Audrey Cilli Adolfo Lutz Institute, Virology Center, Enteric Diseases Laboratory, Av Dr Arnaldo, 355, CEP 01246-902, São Paulo, SP, Brazil Tel: +55 11 30682909; Fax: +55 11 30853505 E-mail: audreycilli@gmail.com |
| Received: June 12, 2013 Accepted: August 28, 2013 Published: September 02, 2013 |
| Citation: Cilli A, Koike CM, Frazatti-Gallina NM, do Carmo Sampaio Tavares Timenetsky M (2013) Detection of Rotavirus G3P[22] Genotype in Gnotobiotic Rabbit Model. J Virol Antivir Res 2:3. doi:10.4172/2324-8955.1000112 |
Abstract
Detection of Rotavirus G3P[22]Genotype in Gnotobiotic Rabbit Model
Rotaviruses have been recognized as important agents of acute diarrhea in both humans and animals. The use of animal models, including the gnotobiotic rabbit, mouse, piglets, lambs and calves models, has been essential to the understanding of rotavirus infection, pathology, disease, immunity, and testing of vaccine prototypes. The aim of this study was to describe the first detection of rotavirus G3P[22] in rabbits in Brazil and to demonstrate the importance of monitoring gnotobiotic animals used in vaccine clinical tests.
