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Chandra Kothapalli

Chandra Kothapalli

Chandra Kothapalli, PhD
Department of Biomedical Engineering
Cleveland State University, USA

 

Biography

Dr. Kothapalli earned Bachelor's degree in Chemical Engineering from Andhra University in India, and Master's degrees in Chemical Engineering and Materials Sciences from Mississippi State University and University of Connecticut, respectively. He received his PhD in Bioengineering from Clemson University in May 2008, where he identified and optimized biomolecular cues comprising extracellular matrix components and growth factors, for regenerating elastin in aortic aneurysmal blood vessels. During his Postdoctoral Fellowship in the Biological Engineering Department at the Massachusetts Institute of Technology, he developed microfluidic assays to evaluate neurite responses to growth factor gradients in vitro, and investigated axonal targeting of projection neurons (e.g.,corticospinal motor neurons) in three dimensional cultures. At MIT, Dr. Kothapalli also identified the role of microenvironment (matrix composition, stiffness, porosity, growth factors) on embryonic stem cell differentiation into various neural and glial lineages, for wide-ranging applications in cell transplantation therapies. His current postdoctoral work on glioblastoma cell migration and proliferation in 3D milieu is funded by the "Emergent Behaviors of Integrated Cellular Systems" grant by NSF at CUNY. So far, Chandra's research has resulted in one patent filing, 22 peer-reviewed publications and proceedings, and more than 30 conference and seminar presentations. Among his numerous honors, he is a member of Sigma XI, and was the Presidential Scholar at the Medical University of South Carolina. He is also excited at the possibility of teaching and mentoring undergraduate and graduate students in chemical and biomedical engineering principles. Dr. Kothapalli holds an Adjunct Staff appointment in the Department of Biomedical Engineering at the Lerner Research Institute in Cleveland Clinic. He is also an Adjunct Assistant Professor in the Division of General Medical Sciences at the Case Western Reserve University School of Medicine.

Research Interest

Dr. Chandra kothapalli's research focuses on Tissue Engineering, Regenerative Medicine, Biologically-inspired Materials, Applied Microfluidics, Stem Cell Therapy, Bioimaging, Nanotechnology in Biomedicine, Cancer biology.

Publications

Use of Autologous Adipose- Derived Stromal Vascular Fraction to Treat Osteoarthritis of the Knee: A Feasibility and Safety Study
Research Article:  J Regen Med 2015, 4:1
doi: 10.4172/2325-9620.1000119
Jaime R Garza, Daniel Santa Maria, Timothy Palomera, Gregory A Dumanian and Severiano Dos-Anjos
Abstract  |   Full-text  |   PDF  |  
Heterogeneity of Stem Cells in Human Amniotic Fluid
Research Article:  J Regen Med 2014, 3:1
doi: 10.4172/2325-9620.1000110
Zhisheng Chen, Michael K Chan, Nicholas Strelchenko, Fang Wang, Li Liu, Mary Ann Perle, Ross S Basch and Bruce K Young
Abstract  |   Full-text  |   PDF  |  
Editors & Editorial Board Members
none:  J Regen Med 2012, 1:1
doi: #
Ernst Reichenberger
Abstract  |   Full-text  |   PDF  |  
Chromatin Topology and Long- Range Genomic Interactions
Editorial:  J Regen Med 2013, 2:2
doi: 10.4172/2325-9620.1000e106
Badam Enkhmandakh and Dashzeveg Bayarsaihan
Abstract  |   Full-text  |   PDF  |  
Editors & Editorial Board Members
none:  J Regen Med 2012, 1:2
doi:
Abstract  |   Full-text  |   PDF  |  
Editors & Editorial Board Members
none:  J Regen Med 2012, 2:1
doi:
Abstract  |   Full-text  |   PDF  |  
Strategic Challenges in Practicing Tissue Engineering and Regenerative Medicine
Review Article:  J Regen Med 2014, 3:2
doi: 10.4172/2325-9620.1000115
Ranjna C Dutta and Aroop K Dutta
Abstract  |   Full-text  |   PDF  |  
Identification and Expansion of Adipose Stem Cells with Enhanced Bone Regeneration Properties
Research Article:  J Regen Med 2016, 5:1
doi: 10.4172/2325-9620.1000124
Di Stefano AB, Leto Barone AA, Giammona A, Apuzzo T, Moschella P, Di Franco S, Giunta G, Carmisciano M, Eleuteri C, Todaro M, Dieli F, Cordova A, Stassi G and Moschella F
Abstract  |   Full-text  |   PDF  |  
2-D Graphene and Derivatives- Based Scaffolds in Regenerative Medicine: Innovative Boosters Mimicking 3-D Cell Microenvironment
Editorial:  J Regen Med 2013, 2:2
doi: 10.4172/2325-9620.1000e107
Farid Menaa
Abstract  |   Full-text  |   PDF  |  
Stem Cells and Management of Healthcare Costs: Stem Cell-Based Treatments and the Societal Balance Sheet
Commentary:  J Regen Med 2016, 5:1
doi: 10.4172/2325-9620.1000125
Michelle Wedemeyer, Samuel Bederman S and Oswald Steward
Abstract  |   Full-text  |   PDF  |  
Nobel Prize to Inducent Pluripotent Stem Cells and Cloning: A Milestone for the Regenerative Medicine
Editorial:  J Regen Med 2012, 1:2
doi: 10.4172/2325-9620.1000e104
Dario Siniscalco, Alessandra Cirillo and Nicola Antonucci
Abstract  |   Full-text  |   PDF  |  
Patent Knowledge and Stem Cell Scientists
Short Communication:  J Regen Med 2014, 3:1
doi: 10.4172/2325-9620.1000111
Amina Agovic
Abstract  |   Full-text  |   PDF  |  
Human Cartilage Tissue Engineering Using Type I Collagen/Heparan Sulfate Scaffolds
Research Article:  J Regen Med 2014, 3:2
doi: 10.4172/2325-9620.1000116
C. Sanjurjo-Rodríguez, A.H. Martínez-Sánchez, T. Hermida-Gómez, I. Fuentes-Boquete, S. Díaz Prado and F.J. Blanco
Abstract  |   Full-text  |   PDF  |  
Why do we know so much about wound healing and yet so little about Keloids?
Editorial:  J Regen Med 2012, 1:1
doi: 10.4172/2325-9620.1000e101
Ernst Reichenberger
Abstract  |   Full-text  |   PDF  |  
Characteristics of Human Amniotic Epithelial Cells and Bone Marrow Mesenchymal Stem Cells in a Parallel Study: Hanging Drop Colony Formation and Doubling Time
Research Article:  J Regen Med 2015, 4:1
doi: 10.4172/2325-9620.1000120
Batool Motamedi, Tengku Azmi Tengku Ibrahim, Ahmad Bustamam Abdul, Zeenathul Nazariah Allaudin, Mojgan Moshrefi, Masoomeh Hajghani and Seyed Noureddin Nematollahi-Mahan
Abstract  |   Full-text  |   PDF  |  
Suspended Life - Stem Cells: Are Treatments Possible?
Editorial:  J Regen Med 2012, 2:1
doi: 10.4172/2325-9620.1000e105
Dario Siniscalco
Abstract  |   Full-text  |   PDF  |  
Regeneration of Cochlear Hair Cells with Atoh1 Gene Therapy after Noise-Induced Hearing Loss
Research Article:  J Regen Med 2015, 4:1
doi: 10.4172/2325-9620.1000121
Andrew K Wise, Brianna O Flynn, Patrick J Atkinson, James B Fallon, Madeline Nicholson and Rachael T Richardson
Abstract  |   Full-text  |   PDF  |  
Human Stem Cell Proliferation and Differentiation: Lessens From a Lost Era of Research
Editorial:  J Regen Med 2013, 2:2
doi: 10.4172/2325-9620.1000e108
Sivan Vadakkadath Meethal, Kentaro Hayashi and Craig S Atwood
Abstract  |   Full-text  |   PDF  |  
Stem Cell Biology and its Role in Regenerative Medicine: A Concept Shaping the Future of Medicine
Review Article:  J Regen Med 2016, 5:1
doi: 10.4172/2325-9620.1000126
Melkamu Bezie, Yonatan Mesfin and Habtamu Biyazen
Abstract  |   Full-text  |   PDF  |  
Tissue Engineering Approaches for Motor Neuron Pathway Regeneration
Review Article:  J Regen Med 2012, 1:2
doi: 10.4172/2325-9620.1000102
Kurt Farrell and Chandrasekhar R. Kothapalli
Abstract  |   Full-text  |   PDF  |  
Stem Cell Therapy for Diabetes: A Call for Efficient Differentiation of Pancreatic Progenitors
Commentary:  J Regen Med 2013 2:1
doi: 10.4172/2325-9620.1000104
Lina Sui, Jing Qu, Fei Yi and Guang-Hui Liu
Abstract  |   Full-text  |   PDF  |  
Platelet-Rich Plasma Therapies:In the Right Pathway to Find their Regulatory Niche
Letter to Editor:  J Regen Med 2014, 3:1
doi: 10.4172/2325-9620.1000112
Eduardo Anitua, Roberto Prado1 and Gorka Orive
Abstract  |   Full-text  |   PDF  |  
Stem Cells and Regenerative Medicine
Editorial:  J Regen Med 2012, 1:1
doi: 10.4172/2325-9620.1000e102
Ian McNiece
Abstract  |   Full-text  |   PDF  |  
Isolation and Purification of Satellite Cells for Skeletal Muscle Tissue Engineering
Review Article:  J Regen Med 2014, 3:2
doi: 10.4172/2325-9620.1000117
Brian C Syverud, Jonah D Lee, Keith W VanDusen and Lisa M Larkin
Abstract  |   Full-text  |   PDF  |  
The Promise of Regenerative Medicine and Stem Cell Research for the Treatment of Autism
Editorial:  J Regen Med 2012, 1:1
doi: 10.4172/2325-9620.1000e103
Dario Siniscalco, James Jeffrey Bradstreet and Nicola Antonucci
Abstract  |   Full-text  |   PDF  |  
Human Stem Cell Derivatives Retain More Open Epigenomic Landscape When Derived from Pluripotent Cells than from Tissues
Research Article:  J Regen Med 2012, 1:2
doi: 10.4172/2325-9620.1000103
Xuejun H. Parsons
Abstract  |   Full-text  |   PDF  |  
Targeted MicroRNA Interference Promotes Postnatal Cardiac Cell Cycle Re-Entry
Research Article:  J Regen Med 2013, 2:2
doi: 10.4172/2325-9620.1000108
Yiqiang Zhang, Noriko Matsushita, Tamar Eigler and Eduardo Marban
Abstract  |   Full-text  |   PDF  |  
Developing Ideal Solution for Acute Wound Treatment by Regenerative Medicine
Case Report:  J Regen Med 2016, 5:1
doi: 10.4172/2325-9620.1000127
Sandeep Shrivastava, Mahakalkar C, Tayde S, Moin Mehmood and Gupta A
Abstract  |   Full-text  |   PDF  |  
Use of Immortalized Differentiated Cells for Regenerative Medicine
Commentary:  J Regen Med 2013 2:1
doi: 10.4172/2325-9620.1000105
John A Loudon
Abstract  |   Full-text  |   PDF  |  
Understanding Somatic (Adult)Stem Cells: Potential vs. Reality
Review Article:  J Regen Med 2014, 3:1
doi: 10.4172/2325-9620.1000113
Kenyon S Tweedell
Abstract  |   Full-text  |   PDF  |  
A Decade after Foetal Skin Progenitor Cell Therapy in Pediatric Burn Treatment
Case Report:  J Regen Med 2015, 4:1
doi: 10.4172/2325-9620.1000122
Anthony de Buys Roessingh, Nathalie Hirt- Burri, Wassim Raffoul, Corinne Scaletta and Lee Ann Applegate
Abstract  |   Full-text  |   PDF  |  
Stem Cell Therapy for Amyotrophic Lateral Sclerosis:Yesterday, Today and Tomorrow
Review Article:  J Regen Med 2014, 3:2
doi: 10.4172/2325-9620.1000118
Murat Kocaoglu, Mevci Ozdemir, Veli Citisli and Kevser Ozdemir
Abstract  |   Full-text  |   PDF  |  
Factors Involved in Tissue Regeneration
Review Article:  J Regen Med 2016, 5:1
doi: 10.4172/2325-9620.1000128
Fatemeh Abedini
Abstract  |   Full-text  |   PDF  |  
Regenerative Potential of Stem Cells for Duchenne Muscular Dystrophy
Commentary:  J Regen Med 2013, 2:2
doi: 10.4172/2325-9620.1000109
Dario Siniscalco and Nataliia Sych
Abstract  |   Full-text  |   PDF  |  
Novel Nanocrystalline Hydroxyapatite for Bone Regeneration
Research Article:  J Regen Med 2014, 3:1
doi: 10.4172/2325-9620.1000114
Orlando Martins, Sérgio Matos, Maria Helena Figueiredo,Carlos Viegas, Isabel Dias, Teresa Vieira, Pedro Nuno Lopes, Isabel Poiares Baptista and Fernando Guerra
Abstract  |   Full-text  |   PDF  |  
Bio-Engineered Mesenchymal Stromal Cell (MSCs) Grafts for Skin Repair/ Regeneration - Preclinical Aspects
Research Article:  J Regen Med 2013, 2:1
doi: 10.4172/2325-9620.1000106
Lucia Formigli, Ferdinando Paternostro, Alessia Tani, Carlo Mirabella, Alessandro Quattrini Li, Daniele Nosi, Riccardo Saccardi, Benedetta Mazzanti, Giulia Lo Russo and Sandra Zecchi-Orlandini
Abstract  |   Full-text  |   PDF  |  
Three-Dimensional Reconstitution of Nerve Blood Vessel Units on Damaged Trachea and Bronchial Stump Using Hybrid-Transplantation of Skeletal muscle-derived stem cells and Bioabsorbable Polyglyconate Felt
Research Article:  J Regen Med 2015, 4:1
doi: 10.4172/2325-9620.1000123
Nakazato K, Tamaki T, Hirata M, Kazuno A Kohno M,Masuda R and Iwazaki M
Abstract  |   Full-text  |   PDF  |  
From Nanotechnology to Epigenomics and Regenerative Medicine
Review Article:  J Regen Med 2012, 1:1
doi: 10.4172/2325-9620.1000101
Dashzeveg Bayarsaihan
Abstract  |   Full-text  |   PDF  |  
Stem Cell Extracellular Matrix Interactions in Three- Dimensional System via Integrins
Research Article:  J Regen Med 2013 2:1
doi: 10.4172/2325-9620.1000107
Jessica M Gluck, Connor Delman, Sean Full, Richard J Shemin and Sepideh Heydarkhan-Hagvall
Abstract  |   Full-text  |   PDF  |  
 
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