International Publisher of Science, Technology and Medicine

Journal of Genetic Disorders & Genetic Reports

Editorial Board

Kenneth Blum

Editor-in-Chief:

Kenneth Blum, PhD  
Department of Psychiatry
University of Florida, USA


Read Interview session with Kenneth Blum

Biography :

Dr. Kenneth Blum (born August 8, 1939) is a researcher on neuropsychopharmacology and genetics. Dr. Kenneth Blum is known from his study on the genetics of alcoholism published in the Journal of the American Medical Association in 1990. Dr. Kenneth Blum works in the fields of neuropsychiatry and genetics, nutritional genetics, and pharmacogenetics. Blum's research has been recognized through numerous awards. Dr. Blum is currently an adjunct full professor in the Department of Psychiatry, University of Florida College of Medicine, and Mcknight Brain Institute (Gainesville, Florida), and formerly of the Department of Physiology & Pharmacology at Wake Forest University School of Medicine (Winston-Salem, North Carolina). Until 2008 he was also Chief Scientific Officer of Salugen, Inc., a personalized health and wellness company in San Diego, California. In 1995 Dr. Kenneth Blum retired as a full professor in the Department of Pharmacology, University of Texas, where he was also chief of the Division of Addictive Diseases, chief of the Division of Substance and Alcohol Misuse, and director of the Laboratory of Pharmacogenetics at the University of Texas Health Science Center (San Antonio, Texas). Currently Dr. Kenneth Blum is the Chairman of the Board and Chief Scientific Officer of LifeGen Inc. (San Diego, California), a neutrigenomic evidence-based corporation.

 Biography
Research Interest :

Dr. Kenneth Blum's research interest includes genetics of alcoholism, neuropsychiatry and genetics, nutritional genetics, and pharmacogenetics.

 Research Interest
Paula Gregory

Editorial Board Members:

Paula Gregory, PhD
LSU Health Sciences Center, USA

Biography :

Dr. Paula Gregory is currently working as a Professor in the Department of Genetics and Department of Cell Biology & Anatomy. Dr. Paula Gregory Director of the Faculty Development Office. Dr. Paula Gregory is a Mississippi native. Dr. Paula Gregory received both her BS and MS. degrees at the University of Southern Mississippi. Her PhD research was carried out at Tulane University on cancer cytogenetics. For her postdoctoral training, she worked with Dr. Bill Brinkley at the University of Alabama at Birmingham. Dr. Paula Gregory's efforts earned her the NHGRI Award of Merit (1994), NIH Director's Award (1997), the NIH Award of Merit (1998) and the Champions of the James Award (2000). Dr. Gregory is also the Director of the Office of Faculty Development for the School of Medicine. Dr. Gregory is the Course Director for the medical Cell Biology and Microscopic Anatomy course for first year medical students. Dr. Gregory is a member of several School of Medicine committees, including: the Women's Affairs Committee, the Faculty Development and Evaluation Committee, the Research Advisory Committee, the Student Promotions Committee and the Junior Faculty Guidance and Mentoring Committee.

 Biography
Research Interest :

Dr. Paula Gregory's research interest includes Biology, Cell Biol and Genetics, cancer cytogenetics, Cell and Molec Bio and Genetics

 Research Interest
Lance A. Liotta

Lance A. Liotta, PhD
George Mason University, USA

Biography :

Dr. Lance A. Liotta is currently Co-Director of the Center for Applied Proteomics and Molecular Medicine. Dr.Lance A. Liotta and Dr.Emanuel F. Petricoin III founded the Center for Applied Proteomics and Molecular Medicine (CAPMM) in 2005. CAPMM is committed to improved, early disease diagnosis; developing individualized and more effective therapies; and creating a new paradigm for personalized patient care. The primary emphasis of disease research is cancer, but new therapies and diagnostics developed in the center apply to cardiology, diabetes, and obesity, as well as liver, ocular, neurodegenerative, and infectious diseases.

 Biography
Research Interest :

Dr. Lance A. Liotta's areas of interest includes Biomedical and Nanoscience.

 Research Interest
Gus Kousoulas K

Gus Kousoulas K, PhD
Division of Biotechnology & Molecular Medicine
Luisiana State University, USA

Biography :

Dr. K. Gus Kousoulas received his BS in Physics from Fairleigh Dickinson University in Teaneck, NJ, and his MS and PhD degrees from Pennsylvania State University in Biophysics and Molecular Cell Biology, respectively. Dr. K. Gus Kousoulas received postdoctoral training at the University of Chicago working in Dr. Bernard Roizman’s laboratory and at the University of California at San Francisco with Dr. Lenore Pereira, where later he was promoted to Research Assistant Professor. Dr. K. Gus Kousoulas joined Louisiana State University in Baton Rouge, LA in 1988 and became full professor in 1994. Dr. K. Gus Kousoulas is currently Professor of Virology at the LSU School of Veterinary Medicine with adjunct appointments at the Department of Biological Sciences, College of Basic Sciences, the Department of Microbiology and Immunology at the LSU Health Sciences Center in New Orleans, and the LSU Health Sciences Center’s Gene Therapy Program and the Stanley S. Scott Cancer Center in New Orleans. He is also an affiliate member of the Tulane National Primate Research Center located in Covington, LA. Dr. Kousoulas has been independently funded by NIH with R01 grants since 1990 working on the molecular biology of herpes simplex virus. Dr. K. Gus Kousoulas is the Principal Investigator of the LSU-Tulane Center for Experimental Infectious Diseases, which is funded by the NIH:NCRR: COBRE mechanism and a mentor of a junior investigator in the LSU Health Sciences Center School of Dentistry COBRE (PI: Paul Fidel). Dr. Kousoulas is a member of the Steering Committee of the LSU Baton Rouge-led NCRR: INBRE program and leads the molecular and cellular biology core of the INBRE. Dr. Kousoulas has served on a number of NIH panels including the NCRR Comparative Medicine Panel and other NIH panels and site visit teams of National Primate Research Centers.

 Biography
Research Interest :

Dr. K. Gus Kousoulas primary research interests are focused on the molecular biology and pathogenesis of herpes simplex viruses (HSV) and human herpesvirus 8 (HHV-8) or Kaposi’s Sarcoma-Associated Herpesvirus (KSHV). Specifically, he seeks to define the molecular mechanisms that control attachment and penetration of these viruses into susceptible cells (including cells of neuronal origin for HSV), their ability to replicate and spread from cell to cell, and the role of membrane fusion events in intracellular virion transport and egress. His experimental approach utilizes advanced molecular biology, molecular genetics and cell biology. Briefly, mutant herpesviruses deficient in a particular function are isolated through generalized mutagenesis, site-specific mutagenesis of viral genomes cloned into bacterial artificial chromosomes (BAC). These engineered viruses are studied to learn about the role of specific virus encoded proteins in host cell attachment, penetration, virus induced cell fusion virion assembly and egress. To analyze the role of specific viral genes in virus penetration and virus-induced cell fusion these genes are expressed in transient, eukaryotic expression systems and the expressed proteins are detected using specific monoclonal antibodies produced in my laboratory. In addition, monoclonal and monospecific sera against viral proteins are utilized to locate their target proteins in infected cells using confocal and immunoelectron microscopy and to analyze their structure and function. A major finding from our studies has implicated multiple protein-protein interactions among viral membrane proteins of both HSV-1 and KSHV in regulation of virus-induced membrane fusion phenomena. Similarly, multiple interactions among membrane proteins and tegument proteins have been found to regulate cytoplasmic virion envelopment. A second major recent interest of his laboratory is the use of viral vectors for gene and ancer therapy and vaccine purposes. Currently funded projects include the generation of oncolytic recombinant herpes simplex virus vectors to combat breast cancer (Louisiana Board of Regents and Louisiana Gene Therapy and Cancer Consortia). These viruses are tested in zenograft mouse models using human breast cancer cells. A significant effort is focused on the production of vaccines for West Nile virus, herpes B virus and Simian Retrovirus using vesicular stomatitis virus (VSV) and adenovirus-based vectors. This work is carried out in collaboration with the Tulane National Research Primate Center (Dr. Preston Marx). A fourth research interest of Dr. K. Gus Kousoulas laboratory is the molecular biology and pathogenesis of human and bovine coronaviruses. Dr. K. Gus Kousoulas has derived and compared the entire genomic nucleotide sequence of several respiratory and enteric bovine coronaviruses and identified specific nucleotide changes, which may be associated with virus tropism. Dr. K. Gus Kousoulas is particularly interested in the structure and function of the viral spike glycoproteins encoded by the SARS coronavirus and respiratory bovine coronaviruses, which are known to promote virus entry into susceptible cells and virus-induced membrane fusion phenomena.

 Research Interest
Barry J Byrne

Barry J Byrne, PhD
University of Florida, USA

Biography :

Dr. Barry J Byrne is currently Director of UF Powell Gene Therapy Center at the same time Professor of Pediatrics and Molecular Genetics & Microbiology and Associate Chair of Pediatrics at University of Florida. Dr. Barry J Byrne's laboratory is focused on understanding the pathophysiology of inherited cardioskeletal myopathies and therapeutic strategies using gene therapy. Specifically, they have developed novel gene therapies for neuromuscular diseases such as Pompe disease. The disease is characteristic of many muscle diseases which lead to skeletal and cardiac muscle weakness. Dr. Barry J Byrne has used AAV vectors to achieve sustained correction of the gene deficiency in Pompe disease models leading to restoration of contractile and metabolic function of striated muscle and motor nerves. Recently, Dr. Barry J Byrne has incorporated novel combinations of AAV serotypes and/or capsid modifications with tissue-specific promoters to direct gene transduction and expression of the therapeutic transgene. Dr. Barry J Byrne approach (AAV) is now being evaluated in a human clinical trial investigating the safety and efficacy of direct gene delivery to the diaphragm.

 Biography
Research Interest :

Dr. Barry J Byrne's research interests includes:

Adeno-associated virus mediated gene transfer in the cardiovascular system and striated muscle, Cell therapy in cardiovascular disease, Gene therapy for muscular dystrophy (Pompe disease and DMD), Mechanisms of allograft tolerance in cardiac transplantation and Cardiac development.

 Research Interest
Linda Pelleymounter

Linda Pelleymounter
Mayo Clinic, USA

Biography :

Dr Linda Pelleymounter from Mayo Clinic, USA made her valuable remarks at International Conference on Biometrics & Biostatistics held during March 5-7, 2012 in Omaha Marriott, USA hosted by OMICS Group Conferences.

 Biography
Research Interest :

Dr. Pelleymounter holds degrees and certificates in multiple fields, including biology, education, german, and diagnostic radiologic technology. She also holds a doctoral degree in music. Dr. Pelleymounter acquired her degrees from Luther College, the University of Texas at Austin, UIHCs and the University of Iowa. Since working in the fi eld of Pharmacogenomics, she has analyzed over 30 human genes and been an author on 22 publications in the field. Dr. Pelleymounter also has SNP discoveries covered by multiple issued patents and a pending patent on a novel methodology for next-generation sequencing analysis. She currently works at the Mayo Clinic, Department of Pharmacology and Experimental Therapeutics, where her primary duty is as a Genomic Research Analyst Technologist.

 Research Interest
Yanmin Yang

Yanmin Yang, PhD
Stanford School of Medicine, USA

Biography :

Dr. Yanmin Yang is currently an Associate Professor of Neurology & Neurological Sciences at Stanford School of Medicine, USA. Dr. Yanmin Yang has also been the member of Bio-X and Child Health Research Institute. Dr. Yanmin Yang has published around 17 articles in various journals related to her field.

 Biography
Research Interest :

Dr. Yanmin Yang research interest includes the following: The cytoskeleton in neurons is made up of three interacting structural complexes: microfilaments (MFs), neurofilaments (NFs), and microtubules (MTs). They serve multiple roles in neurons. First, they provide structural organization for the cell interior, helping to establish metabolic compartments. Second, they serve as tracks for intracellular transport, especially axonal transport, which is critical for neuronal survival. Finally, the cytoskeleton comprises the core framework of neuronal morphologies. Disorganization of the cytoskeleton network is a prominent cytopathological feature of several neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), infantile spinal muscular atrophy (SMA), and Alzheimer diseases. Our major focus is to elucidate biological functions of cytoskeletal associated proteins in neurons and to define the cellular and molecular basis for how these proteins contribute to the structure and function of neurons. Cellular and molecular approaches are being employed both in vitro and in vivo. Our experimental models include:
1) transfection assays,
2) primary neuron cultures,
3) in vitro protein-protein interaction assays,
4) yeast two-hybrid screening,
5) specific gene targeting in mice. Defining the biological functions of cytoskeletal organizing proteins would significantly advance our understanding of pathogenesis of neurodegenerative disorders.

 Research Interest
Momiao Xiong

Momiao Xiong, PhD
Division of Biostatistics
University of Texas School of Public Health, USA

Biography :

Dr. Momiao Xiong has earned various positions at different universities during his professional experience and currently Dr. Momiao Xiong is a Professor of Biostatistics at University of Texas School of Public Health, USA. Dr. Momiao Xiong is also an Adjunct Member of Graduate Faculty at Texas A&M University. Dr. Momiao Xiong has published various articles related to his field of interest in a variety of journal.

 Biography
Research Interest :

Dr. Momiao Xiong's research interests include:

Computational systems biology, functional genomics, bioinformatics, genetic epidemiology, statistical genetics, pharmacogenetics and population genetics

 Research Interest
Arabinda Das

Arabinda Das, PhD
Department of Neuroscience (Neuroscience Research)
Medical University of South Carolina,USA

Biography :

Dr. Arabinda Das is currently working as a Research Assistant Professor in the Department of Neuroscience (Neuroscience Research) at Medical University of South Carolina. Dr. Arabinda Das did his Ph.D. from Utkal University, Bhubaneswar, India. Dr. Arabinda Das has also published various articles in a variety of journal related to his field of interest.

 Biography
Research Interest :

Dr. Arabinda Das research interests includes:

The development of new drugs for cancer treatment and the translation of these findings into clinical trials. Studying glioblastoma multiforme (GBM) and other brain tumors - epigenetic & immunomodulatory activities, novel treatment options, and translational radiation therapy studies.

Understanding the mechanisms and new therapeutic pathways available for the treatment of medial temporal lobe epilepsy (MTLE). Developing translational collaborations for the advancement of epilepsy research.

The development of novel therapeutic strategies for Spinal Cord Injury (SCI), Traumatic Brain Injury (TBI), Glaucoma/Optic Neuritis, and Multiple Sclerosis (MS).

 Research Interest
Li Luo

Li Luo, PhD
Department of Internal Medicine
University of New Mexico, USA

Biography :

Dr. Li Luo is currently an Assistant Professor in the Division of Epidemiology, Biostatistics, and Preventive Medicine, Department of Internal Medicine at University of New Mexico. Dr. Li Luo has published various articles in a variety of journal related to her field of interest.

 Biography
Research Interest :

Dr. Luo’s research interests include statistical genetics and genomics, genetic epidemiology, functional data analysis and high-dimensional data reduction. Dr. Luo’s is specifically interested in developing statistical methods in the areas of gene- and pathway- based genome-wide association studies, integrative analyses of different types of genetic alterations and environmental perturbations involved in complex diseases, and next-generation sequencing (NGS) association analyses utilizing functional data analysis techniques. Currently she is working with Drs. Stidley and Kang on developing statistical methods for NGS studies to detect the association of rare genetic variants with disease or quantitative traits while controlling for other confounding factors including population stratification. Dr. Luo collaborates with Drs. Berwick, Ness, and Cook in identification of genetic factors that are associated with risk and survival of cancer, including melanoma, leukemia, adenoid cystic carcinoma and ovarian cancer.

 Research Interest
Rajinder Kaul

Rajinder Kaul, PhD
University of Washington, USA

Biography :

Dr. Rajinder Kaul is a Research Associate Professor of Medicine at University of Washington.

 Biography
Research Interest :

Dr. Kaul’s current research interests include large-scale DNA sequencing, and he has finished a significant fraction of the human genome and several microbial genomes. He is involved in developing novel technologies for understanding the genetic variations that underlie the phenotypic differences in members of any population. The goal is to carry out Mb range resequencing of targeted regions in genomes from multiple individuals and thereby address basic and clinically relevant biological questions.

 Research Interest
Marlene Shehata

Marlene Shehata, PhD
University of Ottawa, Canada

Biography :

Dr. Marlene Shehata is a part time Professor at the University of Ottawa. Dr. Marlene Shehata is also a Pharmacist and PhD candidate in Genetics of Cardiovascular Diseases.

 Biography
Research Interest :

Dr. Marlene Shehata's main field of research is targeting the salt-sensitive high blood pressure. This particular kind of high blood pressure has been connected with a genetic component that is inherited from parents to offspring and that is usually exacerbated by high salt-intake. As a Geneticist Candidate and a Pharmacist, she is investigating the genes that might be involved in transmitting that genetic form of high blood pressure.

 Research Interest
Joris R. Vermeesch

Joris R. Vermeesch, PhD
Department of Human Genetics
University of Leuven, Belgium

Biography :

Dr. Joris R. Vermeesch is professor Molecular Cytogenetics at the University of Leuven and also faculty member of the European Genetics foundation heading the Constitutional Cytogenetics unit of the Center of Human Genetics, Leuven, Belgium and coordinating the genomic core at the University Hospital. Dr. Joris R. Vermeesch graduated at the University of Nebraska, Lincoln, USA for his studies on telomere biochemistry. Subsequently Dr. Joris R. Vermeesch joined the Center of Human Genetics in Leuven, Belgium during which period he was mainly interested in the structure and evolution of telomeres and centromeres and the development of a human artificial chromosome. Before taking up his current position, Dr. Joris R. Vermeesch was head of the genomics unit in the basic research division of Aventis CropScience and responsible for large scale genome analyses in several crops. Dr. Joris R. Vermeesch is currently president-elect of the Belgium Society of Human Genetics.

 Biography
Research Interest :

Research interests of Dr. Joris R. Vermeesch are: The constitutional cytogenetics laboratory, embedded within the clinical genetics unit of the university hospital, is responsible for the chromosome analysis for preimplantation, prenatal and postnatal diagnosis. Aberrant chromosome number and/or morphology are associated with miscarriages, congenital malformations, developmental disorders, mental retardation, behavioural problems and infertility. The identification of such chromosomal aberrations helps the diagnosis, determines the molecular cause of many disorders and helps family planning in affected families. Besides it’s routine diagnostic activities the laboratory is actively involved in research. The research activities focus on two areas. On the one hand, the laboratory is involved with the development of novel technologies in the area of chromosome analysis and genomics. On the other hand, in collaboration with the clinical geneticists, the laboratory actively seeks to define the molecular causes of developmental, mental and behavioural disturbances. To this end the laboratory takes advantage of the many chromosomal aberrations that are identified in patients and the advent of the human genome project. The international collaborative human genome project has provided us with the sequence of the human genome, the identification of the putative genes within our genome and with the tools to analyse this genome. Using these tools, we can readily analyse chromosomal aberrations at the molecular level and identify the genes causing the observed phenotypic aberrations.

 Research Interest
Mogen Fenger

Mogen Fenger, PhD
Hvidovre University Hospital, Denmark

Biography :

Born on January 11, 951, Dr. Mogen Fenger is currently an Associate Professor and Chief Consultant at Hvidovre University Hospital, Denmark. Dr. Mogen Fenger completed his MD from the University of Copenhagen, Denmark in 1976. Dr. Mogen Fenger has published various articles in a variety of journal related to his field of interest.

 Biography
Research Interest :

Dr. Mogen Fenger's research interests include: Proopiomelanocortin: alpha-amidated and related peptides.

 Research Interest
Sandeep Kumar Kar

Sandeep Kumar Kar, M.D 
Institute of Postgraduate Medical Education & Research, Kolkata, India.

 

Biography :

Dr. Sandeep Kumar Kar is presently working as Assistant Professor, Super specialty department of Cardiac Anaesthesiology, Institute of Postgraduate Medical Education & Research, and Kolkata, India. He has represented India in several world congresses in Anaesthesiology and Critical Care. He has published more than eighty research articles and reviews in high impact international journals including Anaesthesiology (Journal of American Society of Anaesthesiology). He is in the Editorial board of several journals and Editor of Translational Biomedicine, Journal of drug designing, Journal of Bioequivalence and Bioavailability, Journal of Bioanalysis and Medicine, World journal of pharmaceutical Sciences,EJPMR journal and Experimental Cardiology Insight of Blood Pressure, Journal of Neurosurgery, and Interventional Cardiology. He has won several international and National awards like Janak Mehta National Award for best paper in Cardiac Anaesthesiology, B Braun Scholar of the year (2012), ESOP Scholarship (NWAC 2013) and presented papers and lectures in several National and International conferences. He is also a Poet and Writer of international repute with poetry published in several international Journals.

 Biography
Research Interest :

Cardiopulmonary Bypass, Heart Failure, Anaesthetics, Cardiac Surgery, Anaesthesiology, Critical Appraisal Of Research, Poetry Writing, Anesthesiology, Pain, Fictional Works, guitarist, Violinist, Percussionist, Keyboard player, Music therapist, CARDIAC ANESTHESIOLOGY, CRIRICAL CARE, NEURO ANESTHESIOLOGY, LITRETURE, Writing, Anesthesia, Echocardiography, Arrhythmias, Pain Measurement, Catheter Ablation, Valvular Heart Disease, Cardiovascular System, Cardiothoracic Surgery, Pain Perception, Critical Care, Pain Management, Critical Care Medicine, Atrial Fibrillation, Acute Pain, Cardiovascular, Bronchiectasis, Ventilation, ICU, Cardiology, Intensive Care Medicine, Pharmacology, Pain Research, Pain Medicine, Cardiac Arrhythmias, Pain Assessment, General Anesthesia, Cardiac Function

 Research Interest
 
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