Case Report, J Clin Exp Oncol Vol: 6 Issue: 1
Can Medulloblastoma be Presented with Primary Diffuse Leptomeningeal Gliomatosis? Case Report and Literature Review
| Hassoun HK1, Sattar Al-Essawi1, Taki Al Tiraihi2, Aseel A Abdul Wahab3, Amar Saeed Rasheed1, Imad Al-Sabri4 and Zuhair Allebban4* | |
| 1Middle Euphrates Neuroscience Center, Kufa University-College of Medicine, Najaf, Iraq | |
| 2Department of pathology, Terbaite Modares University, Tehran, Iran | |
| 3Department of pathology, Kufa University-College of Medicine, Najaf, Iraq | |
| 4Middle Euphrates Cancer Research Unit, Kufa University-College of Medicine, Najaf, Iraq | |
| Corresponding author : Zuhair Allebban, BVMS, MS, PhD, MB(ASCP), M(ASCP) Director, Middle Euphrates Cancer Research Unit, Professor of Pathology, Kufa University-College of Medicine, P.O. Box 21, Najaf, Iraq Tel: +964 7804272223 E-mail: zuhair.allabban@uokufa.edu.iq |
|
| Received: January 06, 2017 Accepted: January 23, 2017 Published: January 28, 2017 | |
| Citation: Hassoun HK, Al-Essawi S, Tiraihi TA, Wahab AAA, Rasheed AS, et al. (2017) Can Medulloblastoma be Presented with Primary Diffuse Leptomeningeal Gliomatosis? Case Report and Literature Review. J Clin Exp Oncol 6:1. doi: 10.4172/2324-9110.1000175 |
Abstract
Primary diffuse leptomeningeal Gliomatosis (PDLG) is a rare neoplastic condition characterized by primary infiltration of leptomeninges by malignant glial cells which is extremely rare to be as a result of medulloblastoma. To the best of our knowledge, there are only 5 reported localized forms of PDLG cases due to medulloblastoma affecting mainly posterior fossa and/or part of cerebrum. In this article, we are reporting for the first time a case of PDLG with extensive diffuse involvement of leptomeninges due to medulloblastoma extending from the cerebrum to sacral area in 4-year old child presented with acute headache, abducent nerve palsy and papilledema with dramatic response to chemotherapy.
