Cell Biology: Research & TherapyISSN: 2324-9293

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Special Issue Article, Cell Biol Res Ther S Vol: 2 Issue: 0

Clinical Application of Cardiac Stem Cells

Toru Hosoda*
Tokai University Institute of Innovative Science and Technology, Japan
Corresponding author : Toru Hosoda, Ph.D. M.D
Tokai University Institute of Innovative Science and Technology, 143 Shimokasuya, Isehara, Kanagawa 259- 1193, Japan
Tel:
+81-463-93-1121 (Ext. 2784); Fax: +81-463-95-3522
E-mail: hosoda@tokai-u.jp
Received: August 14, 2013 Accepted: November 14, 2013 Published: November 19, 2013
Citation: Hosoda T (2013) Clinical Application of Cardiac Stem Cells. Cell Biol: Res Ther S1. doi:10.4172/2324-9293.S1-001

Abstract

Clinical Application of Cardiac Stem Cells

The recent identification of c-kit-positive cardiac stem cells opened the possibility of their therapeutic usage. In fact, the injection of human cardiac stem cells into the infarcted myocardium resulted in intensive muscle and vessel repair. Based on these animal studies, severe ischemic heart failure patients were treated with their own stem cells in the SCIPIO trial, and the result was outstanding.

Keywords: Cardiac stem cells; C-kit; Cardiac niches; Cardiomyocyte turnover; Myocardial regeneration

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