| Company |
(A) Cell-Inclusive Technologies |
| Condition |
Trade Names (applications) |
| Bionova Int. Pty. Ltd.
www.bionova.com.au |
Vascularization |
Omniflow II (Vascular prosthesis for peripheral revascularization, for arterio-venous access and as vascular patch particularly for carotid patching) |
|
CellMatrix
www.cellmatrix.se |
Cartilage repair (Uses Hyalograft-C HS licensed from Fidia Advanced Biopolymers for culturing autologous chondrocytes.) |
HyCel (Effective & durable Hyaline cartilage repair) |
| Carticel |
| ACT (Autologous chondrocyte transplantation) |
| Celltran Ltd. www.celltran.com |
Burns and wound management |
Myskin (Cultured autologous epidermal substitute for Burns & other skin wounds) |
| Lyphoderm (total lysate derived from cultured keratinocytes for chronic wounds & venous & diabetic leg ulcers.) |
| CytomatrixLLC www.cytomatrix.com |
System for expanding blood stem cells |
TranStem (Autologous blood stem cells for BM transplantation) |
| TransCord (Stem cells from donated umbilical cord blood) |
| RegenImmune (Fresh T cells from blood stem cells) |
| HepaLifeTechnologies Inc. www.hepalife.com |
Bioartificial liver |
HepaMate |
| Interface Biotech A/S www.interfacebio.com |
Cartilage repair |
Cartilink-3 Autologous chondrocyte implantation (ACI) for cartilage defects in the knee |
| Karocell Tissue Engineering www.karocell.com |
Skin equivalents |
Karoskin (Human skin from donors as temporary skin till autologous substitute is available) |
| MatTek
www.mattek.com |
Skin equivalents (Using normal human derived epidermal keratinocytes) |
EpiDerm 201 (Under development) |
| EpidermFT (Full thickness) |
| EpiAirway |
| EpiOcular |
| EpiOral & EpiGingival |
| EpiVaginal |
| Skin equivalents (Using human derived melanocytes) |
MelanoDerm |
| Microislet Inc. www.microislet.com |
Insulin restoration |
MicroIslet-P (Microencapsulated islet cells) |
| Organogenesis Inc. www.organogenesis.com |
Bioactive wound healing |
Apligraf (Bi-layered, bio-engineered living cell based) |
| VCT01 (Bilayered bio-engineered skin with dermal matrix generated de novo from human dermal fibroblast over which human keratinocytes are seeded to form the epidermal layer.) |
| Bio-aesthetics |
Revitix (For skin rejuvination) |
| TestSkin & TestSkin II (For in vitro-skin testing) |
| Bio-Surgery |
FortaFlex FortaPerm (For urology, uro-gynecology & plastic surgeries) |
| FortaGen (For Hernia repair) |
| CuffPatch (For Orthopedics) |
| BioSTAR (FortaFlex incorporated in STARflex, a device to replace the synthetic material) for closure of PFO i.e. patent foramen ovale of the heart. |
| Pervasis Therapeutics Inc.
www.pervasistx.com |
Vascular repair |
Vascugel (Allogenic endothelial cell based therapeutic matrix) |
| SkinEthic Laboratories www.skinethic.com |
Skin equivalents |
EpiSkin: 3D reconstructed human epidermis |
| Tengion Inc./Tengion Technologies
www.tengion.com |
Neo-tissues & Neo-organs (Using autologous committed progenitor cells) |
Neo-Bladder Augment |
| Neo-Vessel Replacement |
| Neo-Kidney Augment |
| Novocell Inc.
www.novocell.com |
Engineered stem cell Endoderm |
For differentiation into the pancreas, liver & other cells, tissue & organs |
| Islet cells incorporated in PEG |
As pancreatic substitute |
| Assays for regenerative medicine & drug |
ADME/toxicity prediction using liver & intestinal cells. |
| Cook Biotech Inc. www.cookbiotech.com |
Hernia repair |
Surgisis Gold |
| IHM (Inguinal Hernia Matrix) |
| Soft Tissue graft |
| Urethral Sling |
Stratasis |
| Stratasis (Tension Free) |
| Wound Matrix |
Oasis |
| Fidia Advanced Biopolymers www.fidiapharma.it |
Osteoarticular |
CartiJoint |
| Hyalgan |
| Hyalubrix |
| Itami |
| Tissue repair (Cosmetic purposes) |
Genaid |
| Hyalofemme |
| Hyal System |
| Hyal-System ACP |
| Hyalosilver |
| Jaloplast |
| Jaloplast Plus |
| Ortek Therapeutic Inc. www.ortekinc.com |
Oral health |
CaviStat (Fluoride-free, cavity fighting complex) |
| Integra Life Sciences www.integra-ls.com |
Integra (Collagen based biomaterial for wound healing) |
Flowable wound matrix |
| Single & Bilayer Matrix Wound Dressing |
| Nerve protector |
NeuraWrap |
| Osteobiologics |
Integra OS (Osteocunductive scaffold) |
| Trel-X (Demineralized Bone Matrix) |
| Orthovita Inc. www.orthovita.com |
Orthobone, OrthoComp (Composite, high strength resin with interface to bond with bone, injectable) |
BioGran (Resorbable, granular biomaterial that transforms to bone) |
| VitaGraft (Injectable, resorbable cement for fracture healing) |
| Vitoss (Calcium phosphate scaffold,a Synthetic Cancellous Bone Void Filler) |
| Cortoss (High strength synthetic cortical bone void filler for use in vertebroplasty) |
| Vitagelb (Surgical hemostat to control bleeding & facilitate healing) |
Rhakoss (Preformed composite, under development) |
| Lifecell
www.lifecell.com |
Tissue Regeneration |
AlloDerm |
| Rapid Vascularization |
Strattice |
| TEI Biosciences www.teibio.com |
General Plastic & Reconstructive surgery |
SurgiMend |
| Burns & wound management |
PriMatrix |
| Neurosurgery |
Durepair |
| Urology & Urogynecology |
Xenform |
| Orthopedics |
TissueMend |
| 3D Biotek
www.3dbiotek.com |
In vitro Research
(PCL and PLGA matrix) |
Culture devices |
| Bio-Tissue Inc.
www.biotissue.com |
Ophthalmic Conformer (Cryo-preserved human amniotic membrane) |
Amniograft (Ocular Wound Therapy) |
| Prokera (Clipped Amniograft into a dual, concave, polycarbonate ring set) |
| Biotissue Technologies www.biotissue-tec.com |
Cartilage repair |
Chondrotissue (Cell-free implant for articular cartilage) |
| Jaw bone repair |
BioSeed-Oral Bone (Jaw-bone transplant) |
| Regentis Biomaterials Ltd. www.regentis.co.il |
Injectable (Investigational Device) |
Gelrin C (Photopolymerizable biodegradable hydrogel) |
| Gelrin B (Void filling matrix for bone regeneration) |
| Tepha Medical Devices www.tepha.com |
Absorbable polymer (P4HB) Devices |
TephaFLEX (Monofilament suture) |
| TephaFLEX (Knitted monofilament Mesh) |
| TephaFLEX (Surgical film) |
| Sewon Cellontech. Co. Ltd. www.RMSbio.net |
RMS-Biocollagen |
Highly purified collagen |
| Atelocollagen Formulations |
Biocollagen Facial Hydrogel Mask |
| RMS-Biocollagen-Liposome |
| Novostrata (For new bio-skin layer) |
| Therafill (Sterile device) |
Dermal Filler |
| ExCel Matrix Biological Devices P. Ltd.
www.excellmatrix.com |
Porous Microparticles
(Tissue filler with or without autologous cells for wound healing) |
PMc Type I |
| PMc Type II |
| Culture Dishes (For in vitro 3D cell culture on cell-interactive scaffold with the convenience of conventional culture method) |
Non-adherent dishes
(For spheroid culture) |
| DotCult |
| ConfoCult |
| Culture Plates (For validated research work on cell-interactive 3D scaffold) |
12-Well DotCult |
| 48-Well DotCult |
| 3D-Inserts (For in vivo graft study on cell-interactive 3D scaffold) |
ECM Grafts |
| Karocell Tissue Engineering www.karocell.com |
Skin equivalents |
Karoderm (Human donated cell free dermis for autologous keratinocytes to grow) |
*An attempt is made to incorporate available Cell-free and Cell-inclusive technologies with their target applications as mentioned on their respective websites. However,
the list may not be exhaustive as newer companies are coming up in this fast developing field.