Atorvastatin Calcium Solubility study Media Solubility (mg/mL) Volume of solvent in mL/1g (mL) USP Solubility scale 0.1N HCl 0.0254 39370.1 Practically insoluble pH 4.5 0.0570 17543.9 Practically insoluble pH 6.8 0.2838 3523.6 Very slightly soluble

Table 2: Atorvastatin Calcium Solubility results.