International Publisher of Science, Technology and Medicine

 

Mark F. Mehler

Mark F. Mehler

Mark F. Mehler
Professor of Neurology,Neuroscience & Psychiatry & Behavioral Sciences
Albert Einstein College of Medicin, USA

 

Biography

Dr. Mehler is currently serving as Alpern Professor and University Chairman, The Saul R. Korey Department of Neurology; Director, Institute for Brain Disorders & Neural Regeneration, Professor of Neurology, Neuroscience & Psychiatry & Behavioral Sciences at Albert Einstein College of Medicine. Dr. Mehler has authored several publications. Dr. Mehler is extensively working with his team on defining the regional localization and the biological properties of neural stem cells during embryonic and postnatal development and in the mature and the aging mammalian brain. We are also using stem cells as "biological probes" to elucidate the pathogenesis of a spectrum of complex and poorly understood acquired and genetic nervous system disorders.

Research Interest

Dr. Mehler's stem cell interests are centered on defining the regional localization and the biological properties of neural stem cells during embryonic and postnatal development, and in the mature and aging mammalian brain. Stem cells are also being utilized as "biological probes" to elucidate the pathogenesis of a spectrum of complex and poorly understood acquired and genetic nervous system disorders. These insights have allowed the laboratory to "reprogram" specific regional stem and progenitor cell subpopulations, both in vitro and in vivo, to acquire the cellular properties of specific neuronal and glial subtypes invariably affected in different classes of neurological diseases. The overall aim of these studies is to identify innovative approaches to brain repair by activation/molecular modulation of latent neural stem cell pools throughout the neuroaxis, and to engage in selective regeneration of those cell types and neural network connections that have been compromised in specific disease states in the adult brain.

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