Alteration in the Global and Regional Left Ventricular and Right Ventricular Myocardial Strain Patterns in Patients with Inferior ST-Elevation Myocardial Infarction Early and Late after Percutaneous Coronary Intervention

Background: Precise evaluation of regional or global heart contractility is very important for the diagnosis, decision of treatment options, and prognosis of clinical outcomes in the Myocardial Ischemia (MI) and infarction.

Aims: Evaluation of the regional or global distortion of Left Ventricle (LV) and Right Ventricle (RV) in cases with Inferior Wall Myocardial Ischemia (IWMI) early and late afterward percutaneous coronary treatment.

Materials and Methods: This prospective study was conducted at Monofia University Hospital during the period from November 2017 till December 2019. The study included patients who presented to the cardiology department with inferior ST Segment Elevation MI (STEMI). Only 40 patients fulfilled the criteria of inclusion and were classified to 2 groups; Group I: include cases suffering from inferior STEMI. Group II (control): 20 healthy volunteer subjects.

Results: This study showed that LV global strain were reduced with highly significant value in cases suffering from IWMI prior to Percutaneous Coronary Intervention (PCI) than in controls (-11.10±1.75 vs -19.84±1.37) P value <0.001 respectively While LV global strain was significantly improved in cases with post-PCI than pre-PCI (-15.86±1.50 vs -11.10 ±1.75) P value < 0.001 respectively.

Conclusion: Reperfusion by PCI outcomes in significant recovery of LV and RV global strains, which are at most exist in the infarct and adjacent myocardium of apical and middle segments.