International Journal of Cardiovascular ResearchISSN: 2324-8602

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Atherosclerotic Burden of Cronaries in DM with MSCT

Background: Multiple studies have confirmed the extensive burden of coronary artery disease in cases with diabetes. Yet, no optimal assessment technique has been proposed for risk stratification of these populations. We performed this study to elucidate the impact of diabetes on the coronary atherosclerotic burden using Coronary Computed Tomography Angiography (CTTA). Patients and methods: This cross-sectional study included 100 cases with coronary atherosclerosis that were divided into two groups; the non-diabetic group 63 cases, and the diabetic group 37 cases. All subjects were subjected to complete history taking, thorough physical examination, and routine preoperative investigations. Additionally, echocardiography and CCTA were done for all cases. Also, calcium score was calculated. Results: The diabetic group displayed significant younger age. However, gender and body mass index did not significantly differ between the two groups. Although smoking prevalence was comparable in the study groups, both hypertension and dyslipidemia had significantly higher prevalence in the diabetic group. Most of the studies echocardiographic variables were comparable between the two groups. The diabetic cases showed a significant increase in both plaque and diseased vessel number. Obstructive lesions were more common in diabetic cases. Calcium score was significantly higher in the diabetic group compared to non-diabetics. Conclusion: It is evident that diabetes is associated with a heavier atherosclerotic burden in the coronary arteries. Additionally, calcium score appears to be a reliable option for assessment of the severity of coronary atherosclerosis.

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