Correlation between Ambulatory Blood Pressure Profile and Left Ventricular Geometry in Egyptian Hypertensive Patients
Background: LVH is one of the sequelae of uncontrolled hypertension which portends a negative impact on both morbidity and mortality. Some studies evaluated the association between ABPM and LVH but data are still not sufficient whether LV geometric changes can be predicted certain parameters from ABPM or not.
Methodology: 150 adults with primary hypertension attending the hypertension clinic in Suez Canal University were studied. Parameters of ABPM were analyzed and correlated with LVH. LV geometric changes. LVMI was calculated by two different methods, one in relation to the body mass index and another in relation to height 2.7.
Results: Patients were divided two groups, dippers and nondippers group. Mean age was 48.9 years with 71.3% were females. According to LVM/BSA, 10% had concentric hypertrophy, 2.7% had eccentric hypertrophy and 24.6% with concentric remodeling. LVH was prevalent in the non-dippers. According to LVM/height 2.7, 18.0% had concentric hypertrophy, 22.0% with eccentric hypertrophy and 14.6% with concentric remodeling. LVH was also more in the non-dippers. According to LVM/BSA, and LVM/height 2.7 patients with concentric hypertrophy had the most elevated SBP, patients with eccentric hypertrophy had the most elevated DBP and patients with concentric remodeling had elevated day-time BP. The significant differences in LV geometry were found in 24- hour and day-time SBP.
Conclusion: There was no statistically significant difference between the different LV geometric patterns between dippers and non-dippers by ABPM. Daytime SBP and 24-h systolic BP elevations were associated with significant differences in LV geometric changes in hypertensive patients.