International Journal of Cardiovascular ResearchISSN: 2324-8602

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Fractional Flow Reserve in Contemporary Clinical Practice

Fractional Flow Reserve in Contemporary Clinical Practice

Percutaneous coronary intervention, guided by angiography, is a well established method of treatment of patients with severe coronary artery disease. However, in patients with intermediate severity lesions, the functional significance of the lesions must be ascertained to avoid unnecessary treatment of non-significant lesions while ensuring treatment of significant lesions. The functional significance of these lesions cannot be assessed by angiography, but can be readily determined by measuring the fractional flow reserve in the artery of interest. Compelling current evidence argues for the use of fractional flow reserve-guided revascularization in these patients.

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