Journal of Immunodeficiency & DisordersISSN: 2324-853X

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Gene Therapy in Primary Immunodeficiencies

Gene Therapy in Primary Immunodeficiencies

Primary immunodeficiencies (PIDs) result from inherited mutations in genes involved in the production, function or survival of specific elements of the immune system (T, B, NK lymphocytes, neutrophils, antigen-presenting cells). Knowing that these elements derive from pluripotent hematopoietic stem cells, it has been tried to use allogeneic hematopoietic stem cell transplantation (HSCT) as an alternative for patients with a PID, which has proven to be an effective  therapeutic approach leading to immune restoration.

Special Features

Full Text


Track Your Manuscript

Media Partners