Journal of Clinical Immunology and Research

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Immunosenescence: Understanding Age-Related Changes in Immune Function

Immunosenescence, the aging-related decline in immune function, is a complex and multifaceted process that profoundly impacts the health and well-being of the elderly population. This manuscript provides a comprehensive review of immunosenescence, exploring the molecular and cellular changes that occur in the immune system with aging. From alterations in immune cell populations to shifts in cytokine profiles and the implications for vaccination and disease susceptibility, the review aims to enhance our understanding of immunosenescence and its implications for the aging population.

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