Neurofibromatosis Type 1 with tumor resection: Case report
Neurofibromatosis type 1 has physical variability or clinical signs associated with the pathology; disease that focal gliomas can occur in the brainstem.
Neurofibromatosis type 1, also known as von Recklinghausen disease, is an autosomal dominant familial tumor syndrome. The incidence of NF1 is about 1 in 3,500 individuals. Low-grade gliomas involving the optic pathway and brainstem are the most common central nervous system neoplasms in patients with NF1. Glioblastoma is a common malignant brain tumor in adults but is a rare occurrence in patients with NF1. We report a rare occurrence of glioblastoma in a 60-year-old man with NF1.