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International Journal of Cardiovascular ResearchISSN: 2324-8602

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Research Article, Int J Cardiovasc Res Vol: 2 Issue: 6

ACP1 Genetic Polymorphism and Cardiac Hypertrophy

Gloria-Bottini F1*, Banci M2, Saccucci P1, Neri A1, Magrini A1 and Bottini E1
1Department of Biomedicine and Prevention, University of Rome Tor Vergata, School of Medicine, Rome, Italy
2Department of Cardiology, Valmontone Hospital, Rome, Italy
Corresponding author : Fulvia Gloria-Bottini
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 100133 Rome, Italy
Tel: ++39+6-30889514
E -mail: [email protected]
Received: October 08, 2013 Accepted: December 19, 2013 Published: December 25, 2013
Citation: Gloria-Bottini F, Banci M,Saccucci P, Neri A, Magrini A, Bottini E (2013) ACP1 Genetic Polymorphism and Cardiac Hypertrophy. Int J Cardiovasc Res 2:6. doi:10.4172/2324-8602.1000151

Abstract

ACP1 Genetic Polymorphism and Cardiac Hypertrophy

Platelet derived growth factors (PDGFs) exert an important role in contractile function of cardiomyocytes and protection from apoptotic cell death. Since ACP1is able to dephosphorylate PDGF receptors modulating their actions we have investigated the relationship between ACP1 genetic variability and cardiac hypertrophy.

Keywords: ACP1; PDGF; Cardiac hypertrophy

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