Opioid dependence could be a diagnosis characterised by a persons inability to prevent victimization opioids (morphine, heroin, codeine, oxycodone, hydrocodone, etc.) even once objectively its in his or her best interest to try and do therefore, and could be a major part of opioid addiction. In 1964 the WHO knowledgeable Committee on Drug Dependence introduced "dependence" as "A cluster of physiological, behavioural and psychological feature phenomena of variable intensity, during which the utilization of a psychoactive substance (or drugs) takes on a high priority. The mandatory descriptive characteristics area unit preoccupation with a need to get and take the drug and chronic drug-seeking behaviour. Determinants and problematic consequences of drug dependence are also biological, psychological or social, and typically interact". The core thought of the WHO definition of "drug dependence" needs the presence of a powerful need or a way of compulsion to require the drug. in line with position papers on the treatment of opioid dependence printed by the world organization workplace on medicine and Crime and also the World Health Organization, care suppliers shouldnt mistake opioid dependence for a weakness of character or can. Accordingly, detoxification alone doesnt represent adequate treatment. Its been incontestable that almost all opioid-dependent patients suffer from a minimum of one severe medical specialty comorbidity. Since opioids employed in pain medical aid seldom cause any of those conditions, theyre assumed to possess existed before the event of dependence. Opioids area unit renowned to possess sturdy antidepressive, anxiolytic and tranquilliser effects and so opioid dependence typically develops as a result of self-medication. Opioids area unit glorious acute pain medication, however its their ability to provide elation that creates them engaging to addicts.