Journal of Marine Biology & Oceanography ISSN: 2324-8661

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Research Article, J Mar Biol Oceanogr Vol: 2 Issue: 3

Anti-Tuberculosis Activity Present in a Unique Marine Bacteria Collection from Portuguese Deep Sea Hydrothermal Vents

Ana Martins1, Gonçalo Andrade1, Cátia Rodrigues1, Ana Almeida1, Ricardo Pinheiro1, Patrícia Calado1 and Helena Vieira1,2*
1BIOALVO, SA TEC LABS-Innovation Center, Campus of FCUL, Campo Grande, 1749-016 Lisbon, Portugal
2University of Lisbon, Faculty of Sciences, Centre for Biodiversity, Functional and Integrative Genomics (BioFIG), Campus of FCUL, Campo Grande, 1749-016 Lisbon, Portugal
Corresponding author : Helena Vieira
BIOALVO, SA TEC LABS-Innovation Center, Campus of FCUL, Campo Grande, 1749-016 Lisbon, Portugal
Tel: +351- 217-500-101; Fax: +351217500220
E-mail: [email protected]
Received: June 04, 2013 Accepted: July 30, 2013 Published: August 06, 2013
Citation: Martins A, Andrade G, Rodrigues C, Almeida A, Pinheiro R, et al. (2013) Anti-Tuberculosis Activity Present in a Unique Marine Bacteria Collection from Portuguese Deep Sea Hydrothermal Vents. J Mar Biol Oceanogr 2:3. doi:10.4172/2324-8661.1000113

Abstract

Anti-Tuberculosis Activity Present in a Unique Marine Bacteria Collection from Portuguese Deep Sea Hydrothermal Vents

Natural product drug discovery from untapped sources of microorganisms, such as the oceans, is full of innovative solutions and is again becoming increasingly explored by the pharmaceutical industry. In fact, interesting bioactivities such as anti-tumour, anti-microtubule and anti-proliferative have been successfully identified in the marine environment. Antibiotic properties of marine products, in particular, have been shown to be effective against several microbial infections and should be further explored for the treatment of infectious diseases such as Tuberculosis, which have become a great threat to global health.

Keywords: Natural products; Tuberculosis; Mycobacterium tuberculosis; Yeast-based screening; Assay development; Marine products; Microorganisms; Mbt panC

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