International Journal of Cardiovascular ResearchISSN: 2324-8602

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Research Article, Int J Cardiovasc Res Vol: 2 Issue: 1

Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers in Asian Indians

Jayashree Shanker1,2*, Satish Govind3, Dhanalakshmi Bhaskar1, Pruthvi Diana Vaz1, Vandana Ravindran4, Vinoth Kumar4 and Vijay Vir Kakkar5,6
1Clinical Research Unit, Thrombosis Research Institute, Bangalore, India
2Mary & Garry Weston Functional Genomics Unit, Thrombosis Research Institute, Bangalore, India
3Non Invasive Cardiology and Echolab, Narayana Hrudayalaya, Bangalore, India
4Elizabeth and Emanuel Kaye Bioinformatics and Statistics Unit, Thrombosis Research Institute, Bangalore, India
5Scientific Chairman and Managing Trustee, Thrombosis Research Institute, Bangalore, India
6President, Thrombosis Research Institute, London, UK
Corresponding author : Dr. Jayashree Shanker
Section-in-charge, Clinical Research Unit, Head, Mary and Garry Weston Functional Genomics Unit, Thrombosis Research Institute, India, 258/A Bommasandra Industrial Area, Anekal Taluk, Bangalore 560099, India
Tel: +91-80-27835303; Fax: +91-80-27835302
E-mail: [email protected]
Received: December 13, 2012 Accepted: January 10, 2013 Published: January 25, 2013
Citation: Shanker J, Govind S, Bhaskar D, Vaz PD, Ravindran V, et al. (2013) Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers in Asian Indians. Int J Cardiovasc Res 2:1. doi:10.4172/2324-8602.1000118

Abstract

Association of Carotid Intima Media Thickness and Periscope Markers with Coronary Artery Disease, Risk factors and Biomarkers in Asian Indians

Surrogate sub clinical markers provide an important dimension to cardiovascular risk stratification. We studied the association of carotid intima media thickness (CIMT) and Periscope markers with CAD, classical risk factors and cardiac biomarkers in a cohort of 125 CAD patients with strong family history of cardiovascular disease and 585 unaffected family members selected from the Indian Atherosclerosis Research Study.

Keywords: Carotid intima media thickness; Periscope; Coronary artery disease; Biomarkers; Asian Indians

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