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Andrology & Gynecology: Current ResearchISSN: 2327-4360

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Review Article, Androl Gynecol Curr Res Vol: 2 Issue: 1

Association of Antisperm Antibodies with Bacterial Infection: An Insight to Infertility

Deepali Thaper, Harpreet Vander and Vijay Prabha*
Department of Microbiology, Panjab University, Chandigarh, India
Corresponding author : Vijay Prabha
Department of Microbiology, Panjab University, Chandigarh 160014, India
Tel: 91-172-2534140; Fax: 91-172-2541770; E-mail: [email protected]
Received: June 26, 2013 Accepted: January 30, 2014 Published: February 05, 2014
Citation: Deepali T, Vander H, Vijay P (2014) Association of Antisperm Antibodies with Bacterial Infection: An Insight to Infertility. Androl Gynecol: Curr Res 2:1. doi: 10.4172/2327-4360.1000118

Abstract

Association of Antisperm Antibodies with Bacterial Infection: An Insight to Infertility

Among other factors, immunological predictors associated with humoral immunity against sperm antigens can be a reason for human infertility. A hypothesis for the induction of antisperm antibodies (ASA) is the cross-reactivity of spermatozoa antigens and exogenous antigens. Common antigenicity has been established between spermatozoa and bacteria, viruses, fungi and allergens. Recent evidence suggests that many antigens shared among unrelated cell types are surface membrane or lipid conjugate complex carbohydrates.

Keywords: Antisperm antibodies; Human infertility; Glycosylation

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