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Acsai M Author
Subjects of specialization
Affiliation
HIV, FAMILY MEDICINE
Maple Leaf Medical Clinic, Canada
Biography
Megan completed an Honours Bachelor of Science at McMaster University in Hamilton Ontario before earning her medical degree in 2007 at the University of Western Ontario. She moved to Vancouver to do her residency in Family Medicine at St Paul's Hospital. After completing residency in June 2009, she did a fellowship in HIV care at the BC Centre for Excellence in HIV/AIDS. She returned to Toronto in July 2010 to build a general family practice with a focus on HIV primary care. She also works as an associate physician at Casey House.
Publications
Research Article Open Access
Impact of Baseline NNRTI Resistance in Antiretroviral-naïve Patients with HIV in A Large Urban Clinic
Author(s): Steinberg S, Loutfy M, Sandler I, Varriano B, Smith G, Kovacs C, Brunetta J, Chang B, Merkley B, Tilley D, Fletcher D, Acsai M, Knox D and Crouzat F
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are prone to baseline resistance and potential early treatment failure. We investigated the NNRTI resistance profiles of antiretroviral therapy (ART)–naive patients with HIV in a large urban clinic and assessed their response to initial ART.
Materials and Methods: This was a retrospective cohort study of ART-naive patients, who had baseline genotypes, starting ART prior to July 16, 2015. Cox regression was used to determine the impact on time to viral suppression with baseline NNRTI resistance as the primary covariate of interest. Of those who achieved virologic suppression, Cox regression was used to determine the impact on viral rebound [viral load (VL) ≥ 200 copies/... view more»
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