Ali El-Sayed Ahmed Author

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Modulation of miRNAs in Aneurysms of the Ascending Aorta: Local versus Circulating Expression Levels

Author(s):

Manfred Richter, Ali El-Sayed Ahmed, Spiros Marinos, Andreas Zierer, Anton Moritz, Andres Beiras-Fernandez and Isabella Werner

Modulation of miRNAs in Aneurysms of the Ascending Aorta: Local versus Circulating Expression Levels

Objective: The identification and treatment of ascending aortic aneurysms (AAA) is still challenging, as the detailed mechanisms leading to AAA formation, progression and rupture, are insufficiently understood. Different miRNAs are known to play important roles in vascular degeneration and the formation of aneurysms in Marfan patients. Thus we investigated the expression profile of miRNAs in patients with AcsAA.

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DOI: 10.4172/2324-8602.1000248

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