Ama Afrah Author

Short Communication Open Access

Reducing inter and intra observer differences using biomarkers in histological diagnosis of invasive cervical cancers and cervical intraepithelial neoplasia in Ghanaian women

Author(s):

Ama Afrah

cancer and cervical intraepithelial neoplasia in women. Criteria for grading of these lesions by pathologist based on digression in growth and degree of invasiveness among other abnormalities have been affected by inter and intra-observer differences resulting in poor reproducibility. Diagnosis disagreement in histopathology between colleague residents or between residents and pathology consultants can result in over/unnecessary treatment that will incur more to a poor woman or under treatment that will put the life of a woman with cervical lesion at risk of metastatic disease with low survival rate. Ki-67, a proliferative marker is useful in grading of cervical cancer and cervical intraepithelial neoplasia by giving uniform and reliable outco... view more»

Abstract PDF