Andrew D. Sparks Author
Subjects of specialization
Affiliation
Surgery
Affiliated to Department of Surgery, George Washington University, Washington DC
He is affiliated to Department of Surgery, George Washington University, Washington DC. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His research interests reflect in his wide range of publications in various national and international journals.
Research Article Open Access
Author(s): Daniel R. King, Katherine L. Januszewicz, Shannon C. Tillery,Molly Shay, Andrew D. Sparks, Danielle Davison,David P. Yamane
Objective: The management of refractory shock remains a challenge with nearly ubiquitous mortality requiring novel therapies to maintain hemodynamics when conventional mechanisms fail. Several exploratory therapies display potential efficacy in the literature, but it remains unclear which therapy is superior. We aim to clarify the efficacy of the current salvage therapies: Angiotensin II (ATII) vs Methylene Blue (MB) vs Vitamin C with thiamine and hydrocortisone (VC) for refractory shock. We hypothesize that these therapies will improve survivability and decrease other vasopressors in patients with refractory shock.
Design: Retrospective chart review.
Setting: Single center mixed intensive care unit (ICU).