Brian C Syverud Author
Subjects of specialization
Affiliation
Enzymatic Dissociation, Biomedical Research, Mechanical Engineering
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA
Brian C Syverud is working at Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. He has a background in both mechanical engineering and biomedical research and am passionate about applying my experience to medical devices.
Review Article Subscription
Author(s): Brian C Syverud, Jonah D Lee, Keith W VanDusen and Lisa M Larkin
Isolation and Purification of Satellite Cells for Skeletal Muscle Tissue Engineering
Engineered skeletal muscle holds promise as a source of graft tissue for the repair of traumatic injuries such as volumetric muscle loss. The resident skeletal muscle stem cell, the satellite cell, has been identified as an ideal progenitor for tissue engineering due to its role as an essential player in the potent skeletal muscle regeneration mechanism. A significant challenge facing tissue engineers, however, is the isolation of sufficiently large satellite cell populations with high purity. The two common isolation techniques, single fiber explant culture and enzymatic dissocia... view moreĀ»