HIV and AIDS Research Journal

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Brunetta J Author

Subjects of specialization
Family Medicine, HIV

Affiliation
Maple Leaf Medical Clinic, Canada

Biography

Jason Brunetta done his Bachelor of Science and Bachelor of Education degrees in Edmonton. He completed  Medical Degree in University of Calgary. His residency in Family Medicine was in Toronto, and then he moved to practice in Vancouver, British Columbia. He has since returned to Ontario and now practices family medicine along with HIV primary care. He is a certificant of the College of Family Physicians of Canada. Dr. Brunetta is also actively involved in research and participates in the education of future physicians by mentoring University of Toronto medical students.


Publications

Research Article Open Access

Impact of Baseline NNRTI Resistance in Antiretroviral-naïve Patients with HIV in A Large Urban Clinic

Author(s):

Steinberg S, Loutfy M, Sandler I, Varriano B, Smith G, Kovacs C, Brunetta J, Chang B, Merkley B, Tilley D, Fletcher D, Acsai M, Knox D and Crouzat F

Background: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are prone to baseline resistance and potential early treatment failure. We investigated the NNRTI resistance profiles of antiretroviral therapy (ART)–naive patients with HIV in a large urban clinic and assessed their response to initial ART.

Materials and Methods: This was a retrospective cohort study of ART-naive patients, who had baseline genotypes, starting ART prior to July 16, 2015. Cox regression was used to determine the impact on time to viral suppression with baseline NNRTI resistance as the primary covariate of interest. Of those who achieved virologic suppression, Cox regression was used to determine the impact on viral rebound [viral load (VL) ≥ 200 copies/... view more»

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