C. Sanjurjo-Rodriacute;guez Author

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Human Cartilage Tissue Engineering Using Type I Collagen/Heparan Sulfate Scaffolds

Author(s):

C. Sanjurjo-Rodríguez, A.H. Martínez-Sánchez, T. Hermida-Gómez, I. Fuentes-Boquete, S. Díaz Prado and F.J. Blanco

Human Cartilage Tissue Engineering Using Type I Collagen/Heparan Sulfate Scaffolds

Introduction: Cartilage engineering may provide a promising alternative solution to current methods of cartilage repair. The aim of this study was to evaluate the suitability of type I collagen (Col I) scaffolds with and without heparan sulfate (HS) to support attachment, proliferation and chondrogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs).

Materials and Methods: hBMSCs were cultured in Col I, Col I+1%HS, Col I+2%HS and Col I+3%HS scaffolds in both chondrogenic and non-differentiation media for 15 ... view more»

DOI: 10.4172/2325-9620.1000116

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