Carlo Mirabella Author

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Bio-Engineered Mesenchymal Stromal Cell (MSCs) Grafts for Skin Repair/ Regeneration - Preclinical Aspects

Author(s): Lucia Formigli, Ferdinando Paternostro, Alessia Tani, Carlo Mirabella, Alessandro Quattrini Li, Daniele Nosi, Riccardo Saccardi, Benedetta Mazzanti, Giulia Lo Russo and Sandra Zecchi-Orlandini

Bio-Engineered Mesenchymal Stromal Cell (MSCs) Grafts for Skin Repair/ Regeneration - Preclinical Aspects

There is growing evidence showing the promise of mesenchymal stromal cells (MSCs) for the treatment of cutaneous wound healing. In a previous study, we have shown that MSCs seeded on an artificial dermal matrix, Integra® enriched with platelet rich plasma (EmatrixTM) have enhanced proliferative potential as compared to those cultured on the scaffold alone. In this study, we wanted to extend the experimentation by evaluating the efficacy of the MSCs bioengineered scaffolds in the healing of skin wounds. To this purpose, full-thickness s... view more»

DOI: 10.4172/2325-9620.1000106

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