Cecilie Paulsrud Author
Subjects of specialization
Affiliation
Philadelphia-negative chronic myeloproliferative neoplasms; , Hypothyroidism; , Hyperthyroidism, Essential thrombocythemia; Polycythemia vera, Autoimmune thyroid disease
Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
Cecilie Paulsrud, MD 2014, is a trainee in internal medicine as part of the basic clinical education blood and hematologic diseases. Published more number of articles which is usefull for blood cancer. Uchiyama T, Yodoi J, Sagawa K
Research Article Open Access
Author(s): Cecilie Paulsrud, Hans C Hasselbalch and Ole Weis Bjerrum
Objectives: Interferon-alpha (IFN-α) is increasingly being used in the treatment of the Philadelphia-negative chronic myeloproliferative neoplasms (MPNs). However, some 20% of patients discontinue treatment because of side effects, including thyroid dysfunction.
Methods: This retrospective study reports patients with MPNs who developed autoimmune thyroid disease (AITD) during treatment with IFN-α, representing 5.0 % of the cohort (n=160).
Results: Eight patients (seven women) developed AITD with positive thyroid peroxidase antibodies. Seven patients had polycythemia vera (PV) and one essentia... view moreĀ»