David P. Yamane Author
Subjects of specialization
Affiliation
Emergency Medicine
Affiliated with George Washington University Hospital and is a Clinical Fellow in Medicine at Brigham and Women's Hospital.
Dr. David Yamane, MD is a board certified emergency medicine physician in Washington, District of Columbia. He is currently licensed to practice medicine in District of Columbia and Massachusetts. He is affiliated with George Washington University Hospital and is a Clinical Fellow in Medicine at Brigham and Women's Hospital.
Research Article Open Access
Author(s): Daniel R. King, Katherine L. Januszewicz, Shannon C. Tillery,Molly Shay, Andrew D. Sparks, Danielle Davison,David P. Yamane
Objective: The management of refractory shock remains a challenge with nearly ubiquitous mortality requiring novel therapies to maintain hemodynamics when conventional mechanisms fail. Several exploratory therapies display potential efficacy in the literature, but it remains unclear which therapy is superior. We aim to clarify the efficacy of the current salvage therapies: Angiotensin II (ATII) vs Methylene Blue (MB) vs Vitamin C with thiamine and hydrocortisone (VC) for refractory shock. We hypothesize that these therapies will improve survivability and decrease other vasopressors in patients with refractory shock.
Design: Retrospective chart review.
Setting: Single center mixed intensive care unit (ICU).