Fady Youssef Author

Editorial Open Access

Aliskiren: Is Combination Therapy with Angiotensin Converting Enzyme Inhibitors(ACE-I) or Angiotensin Receptor Blockers (ARBS) still a Possibility?

Author(s):

Marlene Shehata, Fady Youssef and Alan Pater

Aliskiren: Is Combination Therapy with Angiotensin Converting Enzyme Inhibitors(ACE-I) or Angiotensin Receptor Blockers (ARBS) still a Possibility?

Aliskiren is a blood pressure-lowering agent, which is the first representative of a class of orally active renin inhibitors that directly blocks the Renin-Angiotensin-Aldosterone-System (RAAS) at its rate limiting step. Aliskiren reduces blood pressure by direct renin inhibition and causes a net reduction in plasma renin activity, angiotensin II and aldosterone levels. Aliskiren is marketed in Canada by Novartis under th... view more»

DOI: 10.4172/2324-8602.1000e106

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