Fatemeh Fallah Author

Short Communication Open Access

The antibacterial activity of Zataria multiflora Boiss and Carum copticum on IMP-type metallo-betalactamase-producing Pseudomonas aeruginosa- Fatemeh Fallah- Shahid Beheshti University

Author(s):

Fatemeh Fallah

Aim: Carbapenem resistance due to acquired metallo-beta-lactamases (MBLs) is considered to be more serious than other resistance mechanisms. The aim of this study was to evaluate the antibacterial activity of Zataria multiflora Boiss and Carum copticum plants on IMP-producing P. aeruginosa strains. This experimental study was carried out on hospitalized burn patients during 2011 and 2012. Antibiotics and extracts susceptibility tests were performed by disc diffusion and broth microdilution methods. MBL detection was performed by combination disk diffusion test (CDDT). The bla(VIM) and bla(IMP) genes were detected by PCR and sequencing methods. Using combination disk diffusion test method, it was found that among 83 imipenem resistant P. aeruginosa strains, 48 (57.9%) were MBL producers.... view more»

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