Fatemeh Pourrajab Author
Subjects of specialization
Affiliation
Angioplasty,Aortic valve,Arteriosclerosis,Capillaries,Cardiac arrest
Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Biochemistry and Molecular Biology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran, Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Review Article Open Access
Author(s): Fatemeh Pourrajab, Seyed Khalil Forouzannia and Seyed Hossain Hekmatimoghadam
Molecular Aspects Contributing to Clinical Efficiency of Bone Marrow Stem Cell Transplantation
The multifunctional plasticity of bone marrow derived stem cells represents the most favorable for transplantation. The immunosuppressive properties of BMSCs have been demonstrated on a wide range of innate and adaptive immune cells. BMSC have emerged to be one of the most promising candidates for cellular immunotherapy in solid organ transplantation because the reduction of conventional immunosuppression is highly desirable. Particularly, BMSCs are able to migrate to site of inflammation/ stress to balance the cells through the PI3K/Akt pathway. As well as, BMSCs are exclusivel... view moreĀ»