Journal Plastic Surgery and Cosmetology

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Gail K. Naughton Author

Subjects of specialization
tissue engineering

Affiliation
Histogen, San Diego CA, USA

Biography

Gail K. Naughton, Ph.D., has spent over 30 years researching the tissue engineering process, holds over 105 U.S. and foreign patents, and has founded two regenerative medicine companies. Her current venture, Histogen, is focused on the development of products based on a novel biological platform that replaces and regenerates tissues in the body.


Publications

Short Communication Open Access

E-BABE- Naturally Secreted Growth Factors for Aesthetics: Stimulating Skin and Hair Follicle Stem Cells

Author(s):

Gail K. Naughton

Involved in regulating many cellular processes, growth factors are naturally secreted proteins that support proliferation and differentiation in
cells throughout the body. Intrinsic and extrinsic aging of skin is associated with reduced levels of growth factors that are critical to normal skin
health. A novel bioengineered growth factor composition was developed by Histogen, Inc. utilizing hypoxia-induced human multipotent stem
cells grown in closed suspension bioreactors to produce cell conditioned media (CCM) and has been shown to stimulate mature skin cells and
dermal stem cells and upregulate collagen and elastin production in the body. Topical application of the formulated CCM in a randomized trial
showed statistically significant reduction in the... view moreĀ»

Abstract PDF



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