Gail K. Naughton Author
Subjects of specialization
Affiliation
tissue engineering
Histogen, San Diego CA, USA
Gail K. Naughton, Ph.D., has spent over 30 years researching the tissue engineering process, holds over 105 U.S. and foreign patents, and has founded two regenerative medicine companies. Her current venture, Histogen, is focused on the development of products based on a novel biological platform that replaces and regenerates tissues in the body.
Short Communication Open Access
Author(s): Gail K. Naughton
Involved in regulating many cellular processes, growth factors are naturally secreted proteins that support proliferation and differentiation in
cells throughout the body. Intrinsic and extrinsic aging of skin is associated with reduced levels of growth factors that are critical to normal skin
health. A novel bioengineered growth factor composition was developed by Histogen, Inc. utilizing hypoxia-induced human multipotent stem
cells grown in closed suspension bioreactors to produce cell conditioned media (CCM) and has been shown to stimulate mature skin cells and
dermal stem cells and upregulate collagen and elastin production in the body. Topical application of the formulated CCM in a randomized trial
showed statistically significant reduction in the... view moreĀ»