Ghali Benani Author

Case Report Open Access

Patent Foramen Ovale and Inherited Thrombophilia in the Pathogenesis of Arterial Thrombosis in a Young Patient: A Case Report and Literature Review

Author(s):

El Abasse Zeine, Benmalek Rime, Ghali Benani, Leila Azzouzi and Habbal Rachida

Background: A Patent Foramen Ovale (PFO) is frequently associated with cryptogenic stroke in young patients with paradoxical embolism as the presumed mechanism. Moreover, hypercoagulable states that are known in the pathogenesis of venous thrombosis, can sometimes be found in patients with stroke, which can be explained by the PFO, that provides the missing link. The association between PFO and prothrombotic state may hence increase the risk for paradoxical embolism. Yet, the cause-and-effect relationship between these pathologies is not clearly established and the best therapeutic and preventive strategy are unelucidated. Case Report: We report a case associating ischemic stroke, left internal carotid occlusion, and pulmonary embolism with the discovery of a PFO and inherited thromboph... view more»

DOI: 10.37532/icrj.2021.10(1).429

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