Hany F Hanna Author

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Angiotensin II as an Indicator of Left ventricular Hypertrophy in Uncontrolled Treated Hypertensive Patients

Author(s):

Tamer M Abu Arab, Moustafa El Nozahi, Wessam Wahid and Hany F Hanna

Background: left ventricular hypertrophy (LVH) in uncontrolled hypertension is a major risk factor and the mechanism is not fully understood weather it is due to increased afterload or due to an angiotensin II (Ag II) mediated action on the heart. Objectives: we studied the relationship between Ag II serum level and concentric LVH in patients with hypertension. Methods: a total of 91 patients were included, all had long standing (≥ 5 years) essential uncontrolled treated hypertension and were categorized into two groups according to presence of concentric LVH by echocardiographic criteria (LV mass index (LVMI)>115 g/ m2 for men, LVMI>95 g/m2 for women and relative wall thickness (RWT)>0.42). Group I had 47 patients with LVH and group II had 44 patients without LVH. Ag II ser... view more»

DOI: 10.4172/2324-8602.1000305

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