Hussein Abdellatif Author
Subjects of specialization
Affiliation
Embryology, Anatomy
Anatomy and Embryology Department, Mansoura University, Egypt
Hussein Abdellatif is from Department of Anatomy and Embryology at the Mansoura University, Egypt. Hussein Abdellatif research interest are Oval cells, Partial hepatectomy, Bile duct ligation, OV-6, Flow cytometry, Anatomy, Embryology.
Research Article Subscription
Author(s): Hussein Abdellatif, Mohamed Gamal Shiha
Background: The liver has an impressive capacity for regeneration, However, in cases of severe injury, bipotent progenitors (oval cells) are activated. Such cells are capable of differentiation into hepatocytes and cholangiocytes.
Aim: To detect change in oval cells population in response to partial hepatectomy (PH) and bile duct ligation (BDL) and using a flow cytometric based method.
Methods: 24 female albino rats randomly divided into three groups (A) control, (B) Partial hepatectomy (PH) (C) Bile duct ligation (BDL) group. Animals sacrificed 9 days post injury. Biochemical analysis was performed. Percentage of oval cells in liver t... view moreĀ»