Itemobong Ekaidem Author
Subjects of specialization
Affiliation
Interleukin 25, Systemic lupus erythematous disease activity index, Systemic lupus erythematous, Lupus nephritis
Department of Chemical Pathology, Faculty of Clinical Sciences, College of Health Sciences, University of Uyo, Nigeria
Working at Department of Chemical Pathology, Faculty of Clinical Sciences, College of Health Sciences, University of Uyo, Nigeria; and Institute of Biomedical Research and Innovasions, College of Health Sciences, University of Uyo, Place of living is Nigeria. Subjects of Specialization are Interleukin 25; Systemic lupus erythematous; Lupus nephritis; Systemic lupus erythematous disease activity index
Research Article Open Access
Author(s): Itemobong Ekaidem
Abstract Background: C-reactive protein (CRP) is an inflammatory acute phase protein known to support active immunological responses during infection or tissue injury. Aim: This study aimed to determine the concentrations of CRP, IgM and IgG immunoglobulin isotypes in children with Helicobacter pylori infection with a view to assessing the extent of infection and host immune and inflammatory responses. Method: seventy-four (74) H. pylori sero-positive children were assigned into 3 groups based on their predominant immunoglobulin isotypes, namely Group 1: IgM+ve, Group 2: IgM+ve/IgG+ve and Group 3: IgG+ve. The concentrations of CRP using immunoturbidimetric method, age and body temperature of the children were determined. History of abdominal symptoms were also taken. Results: The result... view moreĀ»