Jonah D Lee Author
Subjects of specialization
Affiliation
Skeletal Muscle, Tissue Engineering, Physiology
Department of Molecular and Integrated Physiology, University of Michigan, Ann Arbor, MI 48109, USA
Jonah D. Lee received the BS degree from the University of Oregon and the PhD degree in the Department of Physical Education, Sport, and Exercise Science from Ball State University, in 2004 and 2010, respectively. He is currently a postdoctoral fellow with the Department of Rehabilitation Sciences, College of Health Sciences and the Department of Physiology, College of Medicine, University of Kentucky.
Review Article Subscription
Author(s): Brian C Syverud, Jonah D Lee, Keith W VanDusen and Lisa M Larkin
Isolation and Purification of Satellite Cells for Skeletal Muscle Tissue Engineering
Engineered skeletal muscle holds promise as a source of graft tissue for the repair of traumatic injuries such as volumetric muscle loss. The resident skeletal muscle stem cell, the satellite cell, has been identified as an ideal progenitor for tissue engineering due to its role as an essential player in the potent skeletal muscle regeneration mechanism. A significant challenge facing tissue engineers, however, is the isolation of sufficiently large satellite cell populations with high purity. The two common isolation techniques, single fiber explant culture and enzymatic dissocia... view moreĀ»