Journal of Chromatography Research

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K Aftab Author

Subjects of specialization
Pharmacology

Affiliation
Professor, Department of Pharmacology. Sialkot Medical College, Pakistan

Biography

Khalid AFTAB worked in few Medical & Dental Colleges & Universities as Assistant, Associate and became full Professor Pharmacology and worked as visiting Professor in different Universities & research institutions. He has worked in Kingdom Saudi Arabia as a full Professor Pharmacology and currently working as Professor & HoD Pharmacology in SMC, University of Health Sciences.


Publications

Short Communication Open Access

Bioassay-Directed Isolation of Hypotensive Alkaloids from Holarrhena Pubescens

Author(s):

K Aftab*, S B Usmani, S Begum and B S Siddiqui

Holarrhena pubescens contains a put to the family Apocynacea, commonly known as “kurchi” is significantly rumored in ordinary pharmaceutical as a remedy for amoebic loose bowels and other intestinal affliction. Bioassay-directed fractionation by chromatographic techniques the ethanolic remove of Holarrhena pubescens brought approximately inside the imprisonment of steroidal alkaloids i.e. Holamide and Pubscinine. Holamide showed up a three proton doublet at 1.45 (J=6.56 Hz) and two AB duplicates at 3.17 and 3.00 each for on proton (J=12.06 Hz) within the 1H NMR extend prescribed that it encompasses a put to cocaine course of action of alkaloid (A lesson of compound with the steroid center and a five people heterocyclic ring with nitrogen).

In separate Pubscinine sh... view moreĀ»

Abstract PDF



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