Liane Deligdisch Author

Short Communication Open Access

Effects of hormone therapy on the uterus

Author(s):

Liane Deligdisch

Hormone therapy is widely prescribed to women of all ages throughout the world. Younger women are using oral contraceptives, or hormonal ovulation stimulation for infertility. Peri- and postmenopausal women are treated with hormone replacement therapy, a controversial issue with challenging new aspects. For breast cancer and uterine neoplastic lesions, there is hormonal adjuvant therapy. The effects on the uterus, especially on the endometrium are multiple, usually prompt and highly versatile due to the presence of binding steroid receptors. The most commonly used hormones are Estrogens (E) and Progesterone (P), normally present and responsible for reproductive functions in premenopausal women. Prolonged and unopposed E may result in abnormal proliferation, hyperplasia and neoplasia of ... view more»

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