Lisa M Larkin Author
Subjects of specialization
Affiliation
Organ Failure, Three-Dimensional (3-D) Engineered Tissues
Department of Molecular and Integrated Physiology, University of Michigan, Ann Arbor, MI 48109, USA
Lisa M Larkin, PhD, is an Associate Professor of Molecular & Integrative Physiology at the University of Michigan. Dr. Larkin holds a joint appointment in the Biomedical Engineering Department at the University of Michigan. Dr. Larkin is co-director of the Skeletal Tissue Engineering Laboratory at the University of Michigan and has 20 years of expertise on musculoskeletal physiology and small animal surgical procedures and more than 10 yearsexperience specifically with ligament,tendon, muscle and bone tissue engineering
Review Article Subscription
Author(s): Brian C Syverud, Jonah D Lee, Keith W VanDusen and Lisa M Larkin
Isolation and Purification of Satellite Cells for Skeletal Muscle Tissue Engineering
Engineered skeletal muscle holds promise as a source of graft tissue for the repair of traumatic injuries such as volumetric muscle loss. The resident skeletal muscle stem cell, the satellite cell, has been identified as an ideal progenitor for tissue engineering due to its role as an essential player in the potent skeletal muscle regeneration mechanism. A significant challenge facing tissue engineers, however, is the isolation of sufficiently large satellite cell populations with high purity. The two common isolation techniques, single fiber explant culture and enzymatic dissocia... view moreĀ»