M. Langhenry1 Author

Research Article Open Access

Clinical outcomes and safety of a combined autologous bone marrow concentrate intraosseous and intraarticular injection for knee osteoarthritis at 12 months

Author(s):

M. Sheinkop1*, M. Langhenry1, D. Curran-Everett3, and T. T. Sand4

Objective:
Safety and therapeutic benefit were assessed for treating knee osteoarthritis with dual intraosseous (tibial plateau)and intraarticular bone marrow concentrate injections. Study participant reported outcomes for Knee Society Score Knee, Knee Society Score Function, Lower Extremity Functional Scale, and Visual Analog Scale were assessed. Outcomes at 1 year were evaluated for influence by study participant factors, including participant demographics, pre treatment clinical outcome values
and bone marrow concentrate cellular composition.
Methods:
Twent y knees with Kellgren Lawrence II III osteoarthritis were treated prospectively at a single site/single investigator in an open label pilot study with autologous bone marrow concentrate. Each participan... view more»

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