Mahmoud A Soliman Author

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Serum Osteopontin as a Predictor of Severity in Patients with Heart Failure: Correlation with Clinical and Echocardiographic Parameters

Author(s):

Mahmoud A Soliman*, Waleed H Abdu, Ashraf Reda, Amro E. Elshabka

Background and objectives: Many biomarkers were recently investigated as possible diagnostic and prognostic makers in heart failure (HF). The authors hypothesized that estimation of serum osteopontin (OPN) level can be a predictor of severity in patients with left sided and right sided heart failure and may be related to clinical and echocardiographic parameters. Methods: Forty patients with left sided HF (group I) (mean age 63.7 ± 6.88), 40 patients with right sided HF (group II) (mean age 59.22 ± 12.12) and 20 healthy individuals (group III) (mean age 57.35 ± 6.40) were included. Measurement of serum brain natriuretic peptide (BNP) and OPN was done. All subjects underwent echocardiography using two-dimensional strain imaging. Left ventricular (LV) and right ventri... view more»

DOI: 10.4172/2324-8602.1000293

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