Journal of Blood Research & Hematologic Diseases

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Manisha M Brahmbhatt Author

ManishaB@gmail.com 646 962 2255

Subjects of specialization
Principle of program, Retinoid, Senescence, ROS, Redox

Affiliation
Department of Cancer Biology, Cell Biology Division, The Gujarat Cancer and Research Institute, NCH Campus, Asarwa, Ahmedabad, Gujarat, India.

Biography

Assistant Professor at National and Kapodistrian University of Athens in Department of Haematology. As a Lecturer and Assistant Professor involved in the training of Hematology Fellows through everyday clinical practice, lectures and courses. Throughout the course of his medical career the focus of his interest was clinical work, in order to provide health services to patients according to the respective positions I held. Theodoros P. Vassilakopoulos has been responsible for the diagnosis and treatment of a significant number of in- and outpatients with a wide variety of hematologic diseases

Publications

Research Article Open Access

Characterization of Complex Chromosomal Rearrangements in Acute Myeloid Leukemia: FISH and Multicolor FISH Add Precision in Defining Abnormalities Associated with Poor Prognosis

Author(s):

Pina J Trivedi, Dharmesh M Patel, Manisha M Brahmbhatt and Prabhudas S Patel

Introduction: The identification of specific chromosome abnormalities in Acute Myeloid Leukemia (AML) is the important for the stratification of patients into the appropriate treatment protocols. However, a significant proportion of diagnostic bone marrow karyotype in AML is reported as normal by conventional cytogenetic analysis. It is suspected that this karyotype may conceal the presence of diagnostically significant chromosome rearrangements. Complex chromosomal aberrations can be detected in a substantial proportion of AML, which are associated with very poor prognosis. Conventional cytogenetic analysis cannot accurately define the specific alterations in Complex chromosomal aberrations. M-FISH al... view more»

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