Mary Ann Perle Author

Research Article Subscription

Heterogeneity of Stem Cells in Human Amniotic Fluid

Author(s):

Zhisheng Chen, Michael K Chan, Nicholas Strelchenko, Fang Wang, Li Liu, Mary Ann Perle, Ross S Basch and Bruce K Young

Heterogeneity of Stem Cells in Human Amniotic Fluid

Amniotic fluid contains a mixture of cells with capacity to differentiate into all germ layers. These cells are present in large numbers in midtrimester samples obtained for cytogenetic diagnosis, and have been identified by stem cell surface markers and transcription factors. We studied cultured samples from patients who had both direct cultures and matched cultures obtained 2 weeks later from the cytogenetics laboratory as well as patients with cytogenetics material only. Samples were cryogenically frozen, thawed, expanded in culture with excellent viability. There was considerable individual variation unrelate... view more»

DOI: 10.4172/2325-9620.1000110

Abstract HTML PDF