Journal of Blood Research & Hematologic Diseases

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Matthew Frome Author

Subjects of specialization
Pisum Sativum pod extract, Department of Curriculum, Senescence

Affiliation
Master's student University of Southern California.

Biography

Matthew Frome, Master's student University of Southern California.Carloc: Precise positioning of automobiles. A collaborative smartphone sensing platform for detecting and tracking hostile drones. Blood typing using serology can provide an inaccurate answer if a patient is recently transfused, taking oncology therapeutics like Darzalex, or has weak or partial antigens. Antisera are not always available for rare antigens. Chronically transfused patients can avoid alloimmunization by receiving antigen-negative blood units


Publications

Perspective Open Access

LinkSeq genotyping: Fast, easy molecular antigen typing

Author(s):

 Matthew Frome

Statement of the Problem:
Blood typing using serology can provide an inaccurate answer if a patient is recently transfused, taking oncology therapeutics like Darzalex, or has weak or partial antigens. Antisera are not always available for rare antigens. Chronically transfused patients can avoid alloimmunization by receiving antigen-negative blood units, but
building a complete patient or donor antigen profile using serology is labor-intensive and can take days. Blood genotyping using traditional methods such as SSP and SSO overcome the limitations of serotyping, but require long, labor-intensive workflows and limited resolution. Blood genotyping using Sanger or NGS sequencing technology have high resolution, but are even more time and labor consuming, expensive and require... view moreĀ»

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