Melkamu Bezie Author
Subjects of specialization
Affiliation
Pathogens, Host Cells
Faculty of Veterinary Medicine, University of Gondar, P.O. Box 196, Gondar,Ethiopia
Melkamu Bezie professional expertise lies in the area of biomedical sciences. He was passionate in molecular interactions between pathogens and host cells. Currently he is investigating on how host cells detect and respond to virus infection.
Review Article Subscription
Author(s): Melkamu Bezie, Yonatan Mesfin and Habtamu Biyazen
Stem cells are special type of cells that have unique capacity to renew themselves and differentiate to give rise to specialized cell types for many tissues. Hence, they are the principal cells of all cell types. Stem cells can be embryonic, fetal, and adult or somatic types. Cells can be reprogrammed artificially through the introduction of endogenous transcription factors by using viruses like retrovirus to produce iPSCs (induced pluripotent stem cells). There are proteins that are important in the regulation of stem cell differentiation such as bone morphogenic protein -2 (BMP-2), leukocyte inhibitory factor and micro RNAs. Cutting edge research featuring stem cells will gear us to medical discovery of cell-based therapies of various diseases occurring in... view moreĀ»