International Journal of Mental Health & PsychiatryISSN: 2471-4372

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Michel Farina-Woodbury Author

michelfarinawoodbury@gmail.com

Subjects of specialization
cAMP; Phosphodiestease; Serotonin; Zembrin extract; Sceletium tortuosum; Alzheimer?s disease

Affiliation
Lawson Health Research Institute, Canada, Department of Psychiatry, University of Puerto Rico, School of Medicine, San Juan, USA

Biography

Dr. Woodbury-Faria graduated from the University of Pennsylvania (1972 Anthropology), The University of Puerto Rico School of Medicine (1976), Flexible Medicine-Surgery Internship at LAC/USC Medical Center (1977), General Psychiatry Residency at Sheppard-Pratt Hospital (1979), Child and Adolescent Psychiatry at Georgetown University Hospital (1981). Post-graduate activities include private practice in Puerto Rico (1982-present), research (1984-present) in psychiatric epidemiology, Phase III Pharmaceutical trials in adult and adolescent schizophrenia and adult depression and nutritional studies on adult schizophrenics (and healthy normals) and academic teaching (1976-present) now Associate Professor at the UPR School of Medicine. Diplomate in Adult, Child and Geriatric Psychiatry.

Publications

Review Article Subscription

Exploring Zembrin Extract Derived from South African Plant, Sceletium tortuosum in Targeting cAMP-driven Phosphodiesterase (PDE) Signaling in Alzheimer’s Disease: Synthesis of Evidence

Author(s):

Simon Chiu, Hana Raheb, Kristen Terpstra, JoshVaughan, Michel Farina-Woodbury, Yves Bureau, Zack Cernovsky, Jirui Hou, John Copen, Mariwan Husni, Vladimir Badmeav, Ana Hategan, Mujeeb Shad, Zach Suntras, Nigel Gericke

Recently with the changing landscape of the aging population and the increase in incidence of Alzheimer’s disease (AD), there has been marked interest to develop strategies to prevent, delay and modify AD. We review the diverse lines of evidence in support of the emerging role of cAMP-mediated Phosphodiesterase (PDE) signalling with respect to aging, inflammation and depression. In view of the link of PDE to Epigenetic complex, targeting PDE through designing modulators and inhibitors of PDE may represent a novel approach in AD therapeutics. We... view more»

DOI: 10.4172/2471-4372.1000104

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